We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen +9 more
wiley +1 more source
First DNA barcode reference library of grasshoppers on the Comoros Archipelago. [PDF]
Wasle PA, Hawlitschek O, Hugel S.
europepmc +1 more source
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song +14 more
wiley +1 more source
Phylogenetic relationship based on DNA barcodes and comparative analysis of phytochemical contents among Rhynchostylis orchids in Thailand. [PDF]
Saengprajak J +5 more
europepmc +1 more source
Sympatric bat species can co‐exist and avoid interspecific competition via niche differentiation e.g. diet. Detecting dietary differences can be achieved by comparing dietary niches of sympatric and allopatric populations. If dietary overlap is higher in sympatry versus allopatry, co‐occurrence may be altering the dietary niche of the species.
Heather Wood +3 more
wiley +1 more source
A Regional DNA Barcode Library for Northern Rocky Mountain Arthropods to Support Biodiversity and Molecular Ecological Research. [PDF]
Seidensticker MT +3 more
europepmc +1 more source
DNA metabarcoding reveals wolf dietary patterns in the northern Alps and Jura Mountains
Understanding predator–prey interactions is crucial for wildlife management and human–wildlife coexistence, particularly in multi‐use landscapes such as western Europe. As wolves Canis lupus recolonize their former habitats, knowledge of their diet is essential for conservation, management and public acceptance.
Florin Kunz +6 more
wiley +1 more source
Rapid assessment of phytoplankton assemblages using Next Generation Sequencing and Barcode of Life Data System: a widely applicable HAB-ID toolkit for detecting and monitoring biodiversity loss and harmful algal blooms. [PDF]
Ivanova NV +6 more
europepmc +1 more source
Urban bats show dietary flexibility in aquatic arthropod consumption at urban and rural waterbodies
Urban waterbodies are critical for biodiversity and provide feeding grounds for insectivorous bats. Yet, how urbanisation affects bats' food choices at urban waterbodies and the role of emergent aquatic arthropods remain poorly understood. We compared the diet of three urban bat species – Vespadelus vulturnus, Chalinolobus gouldii,and Myotis macropus –
Tanja M. Straka +7 more
wiley +1 more source
Validating COI eDNA Metabarcoding Primers for Detection of Subterranean Fauna. [PDF]
van der Heyde M +6 more
europepmc +1 more source

