Results 51 to 60 of about 1,695,496 (296)

DNA barcoding of black flies (Diptera: Simuliidae) in Indonesia

open access: yesParasites & Vectors, 2023
Background DNA barcoding is a valuable taxonomic tool for rapid and accurate species identification and cryptic species discovery in black flies. Indonesia has 143 nominal species of black flies, but information on their biological aspects, including ...
Yan Xin Hew   +12 more
doaj   +1 more source

The promise of a DNA taxonomy [PDF]

open access: yes, 2004
Not only is the number of described species a very small proportion of the estimated extant number of taxa, but it also appears that all concepts of the extent and boundaries of 'species' fail in many cases.
Blaxter, Mark L
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Cryptic diversity of the subfamily Calaphidinae (Hemiptera: Aphididae) revealed by comprehensive DNA barcoding. [PDF]

open access: yesPLoS ONE, 2017
Aphids are a species rich group comprising many important pests. However, species identification can be very difficult for aphids due to their morphological ambiguity. DNA barcoding has been widely adopted for rapid and reliable species identification as
Yerim Lee   +5 more
doaj   +1 more source

jMOTU and Taxonerator: Turning DNA Barcode Sequences into Annotated Operational Taxonomic Units

open access: yesPLoS ONE, 2011
DNA barcoding and other DNA sequence-based techniques for investigating and estimating biodiversity require explicit methods for associating individual sequences with taxa, as it is at the taxon level that biodiversity is assessed. For many projects, the bioinformatic analyses required pose problems for laboratories whose prime expertise is not in ...
Jones, M., Ghoorah, A., Blaxter, M.
openaire   +5 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

DNA barcoding as a complementary tool for conservation and valorisation of forest resources

open access: yesZooKeys, 2013
Since the pre-historic era, humans have been using forests as a food, drugs and handcraft reservoir. Today, the use of botanical raw material to produce pharmaceuticals, herbal remedies, teas, spirits, cosmetics, sweets, dietary supplements, special ...
Angeliki Laiou   +4 more
doaj   +1 more source

Metabarcoding is powerful yet still blind : a comparative analysis of morphological and molecular surveys of seagrass communities [PDF]

open access: yes, 2015
In the context of the sixth wave of extinction, reliable surveys of biodiversity are increasingly needed to infer the cause and consequences of species and community declines, identify early warning indicators of tipping points, and provide reliable ...
Grall, J.   +27 more
core   +2 more sources

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

DNA barcoding deep-water zooplankton from the Gulf of Alaska, North Pacific Ocean

open access: yesFrontiers in Marine Science
DNA barcoding is a method of identifying individual organisms using short DNA fragments matched to a database of reference sequences. For metazoan plankton, a high proportion of species that reside in the deep ocean still lack reliable reference ...
Jennifer M. Questel   +5 more
doaj   +1 more source

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