Results 221 to 230 of about 86,225 (296)

CRISPR‐Based Gene Dependency Screens Reveal Mechanism of BRAF Inhibitor Resistance in Anaplastic Thyroid Cancer

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Anaplastic thyroid cancer (ATC) is the most aggressive form of thyroid cancer. Despite recent advances in treating BRAFV600E‐driven ATC, therapy resistance remains a significant challenge, often resulting in disease progression and death.
Shawn Noronha   +26 more
wiley   +1 more source

Neurodevelopmental Disorder with Dystonia and Chorea Linked to De Novo Variants in the Splicing Regulator SRRM4

open access: yesMovement Disorders, EarlyView.
Abstract Background SRRM4 is an exclusively neural‐expressed splicing‐factor gene not yet associated with a monogenic condition. Objective We sought to delineate movement disorders caused by SRRM4 variants. De novo splice‐donor‐site variants at position +2 of intron 5 of SRRM4 (c.464+2T>C, c.464+2T>A) occurred in three unrelated patients with dystonia ...
Philip Harrer   +24 more
wiley   +1 more source

Sexual reproduction in invasive Japanese knotweed (Reynoutria japonica) in south Sweden

open access: yesNordic Journal of Botany, EarlyView.
To understand the potential for northward expansion of knotweeds into currently uninvaded regions, it is crucial to assess the potential for sexual reproduction alongside the ongoing vegetative spread. For that reason, we tested viability in Reynoutria japonica seeds in south Sweden, a region where viable seeds had not been previously reported ...
Tina D'Hertefeldt   +5 more
wiley   +1 more source

DNA Barcoding Provides Taxonomic Clues for Identifying Five Endangered <i>Phoebe</i> Species in Southern China. [PDF]

open access: yesPlants (Basel)
Yin W   +9 more
europepmc   +1 more source

On the botanical history and nomenclature of the New World genus Piscidia (Fabaceae)

open access: yesNordic Journal of Botany, EarlyView.
Piscidia L. (Fabaceae) is a New World genus with nine recognized taxa (seven species and two varieties). The previous nomenclatural revisions, made in 1910 and in 1969, are revisited here. The names Derris grandifolia Heyde & Lux ex Donn.Sm. and P. cubensis Urb. required step II lectotypifications, with an epitype for the latter name.
Camila Sánchez‐ Vega   +4 more
wiley   +1 more source

Nanopore Sequencing for HPV in Oropharyngeal Squamous Cell Carcinoma and Benign Tonsil Specimens

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objectives Human papillomavirus (HPV) accounts for the majority of oropharyngeal squamous cell carcinoma (OPSCC) cases in the United States but understanding the prevalence of high‐risk HPV in oropharyngeal tissue remains poor. We evaluated nanopore sequencing, a novel rapid, and long‐read sequencing platform, on OPSCC tissue and tested it in ...
Mikayla G. Hubbard   +5 more
wiley   +1 more source

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