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Ultra-sensitive electrochemical DNA biosensor based on a label-free assembling strategy using a triblock polyA DNA probe.

Analytical Chemistry, 2019
Multiblock DNA probe attracted a large amount of scientific attention, for the development of multi-target biosensor and improved specificity/sensitivity.
Lele Wang   +15 more
semanticscholar   +1 more source

Fluorimetric DNA Biosensors

2005
A biosensor is a device that physically combines a biologically active material to a transducer to convert a selective biochemical interaction into a measurable analytical signal The advantages ideally offered by biosensors over other forms of analysis include ease of use (by nonexpert personnel), rapid response, low cost, ease of fabrication, small ...
Paul A. E. Piunno, Ulrich J. Krull
openaire   +1 more source

Towards DNA methylation detection using biosensors

The Analyst, 2016
DNA methylation, a stable and heritable covalent modification which mostly occurs in the context of a CpG dinucleotide, has great potential as a biomarker to detect disease, provide prognoses and predict therapeutic responses.
Leila, Syedmoradi   +2 more
openaire   +2 more sources

Polishable and Renewable DNA Hybridization Biosensors

Analytical Chemistry, 1998
Routine applications of DNA hybridization biosensors are often restricted by the need for regenerating the single-stranded (ss) probe for subsequent reuse. This note reports on a viable alternative to prolonged thermal or chemical regeneration schemes through the mechanical polishing of oligonucleotide-bulk-modified carbon composite electrodes.
Wang, Joseph   +2 more
openaire   +3 more sources

Convective flow effects on DNA biosensors

Biosensors and Bioelectronics, 2007
We explore theoretic limits of convective flux effects, as a function of species concentrations and sample volume, in biosensing systems containing target species with differing affinities. A finite element method is used to simulate mass transport of DNA through a microfluidic chamber to the sensing surface where hybridization of DNA is modeled using ...
J, Bishop, S, Blair, A, Chagovetz
openaire   +2 more sources

An introduction to electrochemical DNA biosensors

The Analyst, 2007
Electrochemical DNA biosensors exploit the affinity of single-stranded DNA for complementary strands of DNA and are used in the detection of specific sequences of DNA with a view towards developing portable analytical devices. Great progress has been made in this field but there are still numerous challenges to overcome. This review for researchers new
Katherine J, Odenthal, J Justin, Gooding
openaire   +2 more sources

Disposable Electrochemical DNA Biosensors

2004
Electrochemical DNA hybridization biosensors have been a major research field for over a decade, because their rapid, simple, and low-cost detection capabilities provide several advantages to clinical, forensic, and environmental monitoring. Basically, DNA biosensors convert the Watson-Crick base-pair recognition event into a readable analytical signal.
Kerman K., Ozsoz M.
openaire   +2 more sources

New DNA Technology and the DNA Biosensor

Analytical Letters, 1987
Abstract Recently there has been an increasing demand to produce systems for the detection of specific DNA sequences that are amenable to non-specialised laboratories. This demand has led to many innovative and novel approaches to DNA analysis which may collectively be termed ′new DNA technology′.
Mark E A Downs   +2 more
openaire   +1 more source

A ratiometric electrochemical DNA-biosensor for detection of miR-141

Microchimica Acta, 2022
A. Khodadoust   +5 more
semanticscholar   +1 more source

Charge Transfer through DNA: A Selective Electrochemical DNA Biosensor

Analytical Chemistry, 2006
The charge-transfer properties of DNA duplexes are exploited to produce a fast, simple, sensitive, and selective DNA biosensor by exposing the DNA recognition interface to a sample containing target DNA and the redox-active intercalator, anthraquinonemonosulfonic acid (AQMS).
Wong, ELS, Gooding, JJ
openaire   +3 more sources

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