Results 91 to 100 of about 794,185 (285)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Constructing DNA Codes with Larger Distance from Quaternary Words

open access: yesJambura Journal of Mathematics
In this work, we propose a novel method to construct DNA codes from quaternary words. The method uses permutation groups that act in the set {1, 2, …, 4n}, representing the coordinate and coordinate value of quaternary words.
Benediktus Panji Pradipta   +1 more
doaj   +1 more source

Recognition Code of ZNF191(243-368) and Its Interaction with DNA

open access: yesBioinorganic Chemistry and Applications, 2015
ZNF191(243-368) is the C-terminal region of ZNF191 which contains a putative DNA-binding domain of four Cys2His2 zinc finger motifs. In this study, an expression vector of a fusion protein of ZNF191(243-368) with glutathione-S-transferase (GST) was ...
Dongxin Zhao, Zhongxian Huang
doaj   +1 more source

DNA-Correcting Codes in DNA Storage Systems

open access: yesCoRR, 2023
In [1], the authors proposed a new model of DNA storage system that integrates all three steps of retrieval and introduced the concept of DNA-correcting codes, which guarantees that the output of the storage system can be decoded to the original data. They also gave necessary and sufficient conditions for DNA-correcting codes when the data part is free
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Unlocking the chromatin code by deciphering protein–DNA interactions

open access: yesMolecular Systems Biology, 2016
Characterizing the composition of protein complexes bound to different genomic loci is essential for advancing our mechanistic understanding of transcriptional regulation.
Dalila Bensaddek, Angus I Lamond
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

DNA Code from Cyclic and Skew Cyclic Codes over F4[v]/〈v3〉. [PDF]

open access: yesEntropy (Basel), 2023
Prakash O   +4 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Food Anti-counterfeiting and Traceability Based on DNA Storage: Technology, Challenges and Prospects [PDF]

open access: yesShipin Kexue
Food anti-counterfeiting and traceability are important ways to ensure food safety. In response to the upgrading of counterfeiting means, a variety of identification technologies have been gradually developed, which play a crucial role in the field of ...
SONG Yafeng, XING Ranran, LIANG Xiaoke, GONG Na, ZHEN Zixuan, ZHANG Jiukai, CHEN Ying
doaj   +1 more source

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