Results 231 to 240 of about 1,155,163 (294)

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Finding a role for non-coding DNA in trypanosomes. [PDF]

Elife
Schmidt MR.
europepmc   +1 more source

IL‐3 Modulates Microglia Polarization and Attenuates Neuroinflammation in Traumatic Brain Injury

Advanced Science, EarlyView.
IL‐3 recruits PRDX1 through IL‐3R to modulate the inflammatory response of microglia via the KEAP1‐NRF2‐HO‐1/NF‐κB pathway to attenuate neuroinflammation in traumatic brain injury. ABSTRACT Microglia play a crucial role in the progression of neuroinflammation following traumatic brain injury (TBI). Interleukin‐3 (IL‐3), a significant regulatory factor,
Nana Huang, Qingchen Zhang, Yanrui Chen, Dapeng Yu, Ronghan Liu, Jianning Kang, Xiang Fang, Ying Zhang, Hong Bian, Yanxin Zhao, Yongcheng Yin, Ce Zhang, Yanfei Jia, Qingfa Chen, Yuepeng Fang, Shang Li, Fang Li, Zhengxin Jin, Bin Ning   +18 more
wiley   +1 more source

The complete chloroplast genome of <i>Boehmeria tricuspis</i> (Urticaceae). [PDF]

Mitochondrial DNA B Resour
Lan C, Han Y, Yang C, Li T, Dong J.
europepmc   +1 more source

Advances in epigenetic therapy for esophageal cancer. [PDF]

Clin Epigenetics
Ye C, Yan X, Gao Y.
europepmc   +1 more source

A high-quality chromosome-level genome assembly of the low chilling requirement mulberry, Morus macroura. [PDF]

Sci Data
Wu H, Wang J, Geng T, Yao Y, Lin P, Wang S, Xu L.   +6 more
europepmc   +1 more source

The complete mitogenome of <i>Calappa japonica</i> ortmann, 1892 (Decapoda: Calappidae) from the East China Sea. [PDF]

Mitochondrial DNA B Resour
Zhao XX, Fang YF.
europepmc   +1 more source

Epigenetic modifications in ferroptosis regulation of breast cancer. [PDF]

Am J Cancer Res
Lin L, Wang Y, Si W, Liu X.
europepmc   +1 more source

Introns as Protective Buffers Against Transposable Elements Invasion During Genome Gigantism in a Newt. [PDF]

Genes Cells
Bou K, Agata K.
europepmc   +1 more source