Results 161 to 170 of about 4,801,647 (345)

Mechanisms of DNA damage, repair, and mutagenesis

Environmental and Molecular Mutagenesis, 2017
Nimrat Chatterjee, G. Walker
semanticscholar   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Repair of Ultraviolet Light Damage to the DNA of Cultured Human Epidermal Keratinocytes and Fibroblasts

, 1979
Lorne B. Taichman, R. B. Setlow
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage. [PDF]

, 1989
Robert H. Schiestl, Paul R. Reynolds, Satya Prakash, Louise Prakash   +3 more
openalex   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Damage of DNA and its recovery in AH-109A cells treated with carboquone in vivo.

, 1978
Ryunosuke Kanamaru, M Asamura, Yoshito Hayashi, Haruhiko Sato, Tatuo Saito   +4 more
openalex   +2 more sources

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Action Spectrum of Ultraviolet Light-Induced Damage to Nuclear Dna In Vivo**From the Department of Experimental Pathology and the Division of Dermatology, Scripps Clinic and Research FoundatiOn, La Jolla, California 92037 and the Department of Pathology, University of Texas, Southwestern Medical School, Dallas, Texas 75235.

, 1970
Eng M. Tan, Robert G. Freeman, Richard B. Stoughton   +2 more
openalex   +1 more source

DNA damage related to increased hydrogen peroxide generation by hypolipidemic drug-induced liver peroxisomes. [PDF]

, 1984
William E. Fahl, Narendra D. Lalwani, Takafumi Watanabe, Sonia Goel, Janardan K. Reddy   +4 more
openalex   +1 more source