Results 171 to 180 of about 4,801,647 (345)

ROS and the DNA damage response in cancer

Redox Biology, 2018
U. S. Srinivas, B. Tan, B. Vellayappan, A. Jeyasekharan   +3 more
semanticscholar   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Direct Evidence that Damaged DNA Results in Neoplastic Transformation—A Fish Story

, 1975
R. B. Setlow, Ronald W. Hart
openalex   +2 more sources

A highly conserved endonuclease activity present in Escherichia coli, bovine, and human cells recognizes oxidative DNA damage at sites of pyrimidines. [PDF]

, 1987
Paul W. Doetsch, W. David Henner, Richard P. Cunningham, J. H. TONEY, Dag E. Helland   +4 more
openalex   +1 more source

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response.

Molecules and Cells, 2017
Andrew N. Blackford, S. Jackson
semanticscholar   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Growth arrest is a DNA damage protection strategy in Arabidopsis. [PDF]

Nat Commun
Serrano-Mislata A, Hernández-García J, de Ollas C, Blanco-Touriñán N, Jurado-García S, Úrbez C, Gómez-Cadenas A, Sablowski R, Alabadí D, Blázquez MA.   +9 more
europepmc   +1 more source

Photorepair of uv damage to DNA: studies with the DNA-photoreactivating enzyme. Three year summary, January 2, 1970--April 31, 1973

, 1973
Harold Werbin
openalex   +2 more sources

Nitroaromatic radiation sensitizers substitute for oxygen in neocarzinostatin-induced DNA damage. [PDF]

, 1984
Lizzy S. Kappen, I. Goldberg
openalex   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source