Results 191 to 200 of about 1,557,993 (359)

RPA1 protects DNA damage-induced PANoptosis in limb development. [PDF]

open access: yesSci Adv
Yin Q   +11 more
europepmc   +1 more source

Signalling DNA Damage

open access: yes, 2012
Lopez-Contreras, Andres Joaquin   +1 more
openaire   +3 more sources

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

open access: yesFEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

Cholangiocytes' primary cilia regulate DNA damage response and repair. [PDF]

open access: yesAm J Physiol Gastrointest Liver Physiol
Peixoto E   +6 more
europepmc   +1 more source

Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells. [PDF]

open access: green, 1989
Albert J. Fornace   +3 more
openalex   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

open access: yesFEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno   +12 more
wiley   +1 more source

Hydroxyl radical production and DNA damage induced by anthracycline‐iron complex [PDF]

open access: bronze, 1984
Josephia R. Muindi   +3 more
openalex   +1 more source

An optimized protocol to detect high‐throughput DNA methylation from custom targeted sequences on 96 samples simultaneously

open access: yesFEBS Open Bio, EarlyView.
Workflow of a high‐throughput technology for epigenotyping of differentially methylated CpGs in specific regions of the genome. The protocol works with small amounts of DNA extracted from blood or semen. The protocol consists of both enzymatic conversion of unmethylated cytosines and capture by hybridization with a custom panel.
Nathalie Iannuccelli   +4 more
wiley   +1 more source

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