Results 311 to 320 of about 5,698,803 (355)

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

ATR, a DNA damage kinase, modulates DNA replication timing in Leishmania major. [PDF]

PLoS Genet
da Silva GLA, Damasceno JD, Black JA, Lapsley C, McCulloch R, Tosi LRO.   +5 more
europepmc   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Dissecting the Biological Functions of Various Isoforms of Ferredoxin Reductase for Cell Survival and DNA Damage Response. [PDF]

Cells
Nakajima KI, Mohibi S, Hong K, Chen X, Zhang J.   +4 more
europepmc   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Rapamycin Exerts Its Geroprotective Effects in the Ageing Human Immune System by Enhancing Resilience Against DNA Damage. [PDF]

Aging Cell
Kell L, Jones EJ, Gharahdaghi N, Wilkinson DJ, Smith K, Atherton PJ, Simon AK, Cox LS, Alsaleh G.   +8 more
europepmc   +1 more source

FBXW7-mediated CHK2 regulation modulates DNA damage response and cellular stability in Huntington's disease. [PDF]

Cell Death Discov
Kang TE, Lee YM, Choi SH, Cho K.
europepmc   +1 more source

Telomeric DNA damage landscapes distinguish oxidative from inflammatory cellular stress. [PDF]

Nucleic Acids Res
Fleming AM, Burrows CJ.
europepmc   +1 more source

Advances in DNA damage detection: Current progress, challenges, and future directions

Heeseok Kang, Hyung Joon Park, Jieun Kang, Y.K. Hwang, Yongjin Lee, Sang-Uk Park, Jong-Chill Kim, Kwan H. Lee, Sunbok Jang   +8 more
openalex   +1 more source

DNA damage-dependent mechanisms of ionizing radiation-induced cellular senescence. [PDF]

PeerJ
Guan J, Li T, Ma F, Wang N, Zhang H, Li J, Li J, Xu C, Liu Q.   +8 more
europepmc   +1 more source