Results 31 to 40 of about 557 (121)
Abstract Cabled multiparametric observatories are sustaining ecological monitoring by collecting long‐term real‐time biological and environmental data. Here, we investigated fish communities by sampling environmental DNA (eDNA) over 4 days near the multiparametric cabled video‐observatory OBSEA (Northwestern Mediterranean Sea).
Maddalena Tibone +7 more
wiley +1 more source
Auxin response and PIN‐mediated transport in chlorophyte algae
Like multicellular plants, green algae respond to auxin and move it across their cells. However, their PIN‐like proteins do not act like plant auxin exporters, suggesting that basic auxin transport evolved early and specialized directional transport appeared later in plant evolution.
Adrijana Smoljan +11 more
wiley +1 more source
NbRD21 protease controls receptor kinase homeostasis in Nicotiana benthamiana
Proteomic analysis revealed that receptor kinases (red) accumulate higher in rd21 knockout Nicotiana benthamiana plants. Summary RD21‐like proteases are papain‐like cysteine proteases with a C‐terminal granulin domain that are abundant and ubiquitous in angiosperms and have often been implicated in immunity.
Alice Godson +13 more
wiley +1 more source
ABSTRACT Triticale (x Triticosecale Wittmack) is an interspecific hybrid of wheat and rye. It is a promising grain and forage crop that thrives in poorer soils and low‐input farming systems. It can serve as a viable alternative to traditional small grains such as wheat and barley, bringing diversity to crop rotations and enhancing biodiversity in ...
Riccardo Zustovi +17 more
wiley +1 more source
MEF2B and BCL6 have established functions in germinal center B‐cell biology and lymphomagenesis. The mechanism of MEF2B deregulation and its significance for cell survival in Burkitt lymphoma however remain unclear. This study highlights MEF2B as a crucial transcription factor in Burkitt lymphoma and suggests ZDHHC11 as an upstream regulator of MEF2B ...
Lotteke J. Y. M. Ziel‐Swier +12 more
wiley +1 more source
Applications and limitations of AI tools in enzyme design
Abstract Enzymes catalyze various different chemical reactions often with high efficiency and selectivity compared to synthetic catalysts. Advances in protein engineering over the past decades have allowed researchers to design enzymes, improving their catalytic performance and adapting them for specific or entirely novel chemical reactions.
Rosa Teijeiro‐Juiz +6 more
wiley +1 more source
We synthesized GPS telemetry, genetic, and pathogen data to evaluate metapopulation processes in a reintroduced Rocky Mountain bighorn sheep (Ovis canadensis canadensis) population in Dinosaur National Monument. We estimated subpopulation‐specific abundances and found 4 small subpopulations with high genetic diversity, partial connectivity, and ...
Sarah L. Carroll +8 more
wiley +1 more source
Aminoferrocene‐based prodrugs represent a promising class of redox‐active anticancer agents that can be selectively activated in oxidative cellular environments. However, activation of these systems typically relies on reactive oxygen species (ROS) and is therefore inefficient in intracellular compartments with low ROS levels, such as the cytoplasm. In
Hülya Gizem Özkan +5 more
wiley +1 more source
The 10B‐enriched monocarbonyl analog of curcumin (BMAC) 10B‐9 enables site‐specific Boron Neutron Capture Therapy (BNCT) on amyloid‐β (Aβ) fibrils. Neutron irradiation induces histidine oxidation and fibril destabilization, as revealed by 1H‐NMR and FESEM analyses.
Sebastiano Micocci +13 more
wiley +1 more source
Coenzyme Acceptance in Ene‐Reductases From Herbaspirillum seropedicae
Ene‐reductases HSI and HSII from the beta‐proteobacterium Herbaspirillum seropedicae show promiscuity towards the coenzymes NADH and NADPH and efficiently reduce maleimides. Ancestral sequence reconstruction, kinetic characterisation and structural analysis suggest that oligomerisation contributes to the evolution of coenzyme acceptance. Ene‐reductases
Karishma Shah +6 more
wiley +1 more source

