Results 121 to 130 of about 2,699,979 (303)

p185neu encoding DNA and therapeuticaluses thereof

, 2010
Plasmids containing sequences encoding different fragments of p185neu oncoprotein, able to induce an immune response against tulours expressing oncogenes of the ErbB family, and pharmaceutical compositions thereof.
AMICI, Augusto, MARCHINI, Cristina, Federica Cavallo, Guido Forni   +3 more
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Enhanced osteoarthritis therapy by nanoengineered mesenchymal stem cells using biomimetic CuS nanoparticles loaded with plasmid DNA encoding TGF-β1. [PDF]

Bioact Mater, 2023
Cai Y, Wu C, Ou Q, Zeng M, Xue S, Chen J, Lu Y, Ding C.   +7 more
europepmc   +1 more source

Results from qPCR for carbapenemase-encoding genes using DNA directly extracted from faecal samples.

Results from qPCR for carbapenemase-encoding genes using DNA directly extracted from faecal samples.
Luca Belleggia (9160371), Cristiana Cesaro (17743293), Serena Simoni (5445434), Carla Vignaroli (407543), Giorgia Rampanti (17743299), Andrea Brenciani (5445425), Lucia Aquilanti (5986007), Vesna Milanović (5985983), Cristiana Garofalo (5985989), Federica Cardinali (5985986), Marina Pasquini (6288863), Maria Federica Trombetta (6288875), Tullia Matricardi (17743296), Andrea Osimani (5985980)   +13 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Expression of genes encoding chromatin-modifying proteins that could potentially contribute to the “random” DNA methylation.

, 2013
Expression of genes encoding chromatin-modifying proteins that could potentially contribute to the “random” DNA methylation.
Yadong Wang (82064), Curt Balch (330531), Lang Li (91927), Mingxiang Teng (245080), Kenneth P. Nephew (212536), Yunlong Liu (46477), Tim H. M. Huang (133129), Meng Li (79487)   +7 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Influence of Recombinant Codon-Optimized Plasmid DNA Encoding VEGF and FGF2 on Co-Induction of Angiogenesis. [PDF]

Cells, 2021
Salafutdinov II, Gazizov IM, Gatina DK, Mullin RI, Bogov AA, Islamov RR, Kiassov AP, Masgutov RF, Rizvanov AA.   +8 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Gemini Cationic Lipid-Type Nanovectors Suitable for the Transfection of Therapeutic Plasmid DNA Encoding for Pro-Inflammatory Cytokine Interleukin-12. [PDF]

Pharmaceutics, 2021
Sánchez-Arribas N, Martínez-Negro M, Aicart-Ramos C, Tros de Ilarduya C, Aicart E, Guerrero-Martínez A, Junquera E.   +6 more
europepmc   +1 more source