Results 251 to 260 of about 4,873,130 (388)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The extraction of DNA efficiency of pedunculate oak (Quercus robur L.) and silver birch (Betula pendula Roth.) organs and tissues using different methods

И.В. Ромашкина, E.V. Selivanova, Анна Попова, Vadim G. Lebedev, Konstantin A. Shestibratov   +4 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Detection of Some SalmonellaEnteritidisVirulence Genes by Multiplex-PCR Assay Using Two Different DNA Extraction Methods

, 2017
Kareem Thamir Al-Kaaby, Ahmed H. Al-Dabhaw, Hayder M. Samaka   +2 more
openalex   +2 more sources

An optimized DNA extraction protocol for reliable PCR-based detection and characterization of grapevine flavescence dorée phytoplasma. [PDF]

Plant Methods
Carli M, Pedrelli A, Panattoni A, Pellegrini E, Nali C, Cotrozzi L, Rizzo D.   +6 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

The Latest Practices in Culture-Free Detection of Bacteria in Water, From Sampling to Membrane Filtration and DNA Extraction: A Systematic Review. [PDF]

Microbiologyopen
Togănel RO, Ciurea CN, Cighir A, Mare AD, Coșeriu RL, Vintilă C, Cucoranu DC, Man A.   +7 more
europepmc   +1 more source

Gut Microbiota Analysis Results Are Highly Dependent on the 16S rRNA Gene Target Region, Whereas the Impact of DNA Extraction Is Minor.

Journal of Biomolecular Techniques, 2017
Anniina Rintala, S. Pietilä, E. Munukka, E. Eerola, J. Pursiheimo, A. Laiho, S. Pekkala, P. Huovinen   +7 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Simple and Rapid DNA Extraction from Tofu and Soy Milk for the Detection of Contaminating GMO

, 2007
Kappei Kobayashi, Ikuko Munemura, Hirofumi Uchimiya, Saburo Yamamura   +3 more
openalex   +2 more sources