Results 251 to 260 of about 4,713,939 (389)

Interlaboratory evaluation of high molecular weight DNA extraction methods for long-read sequencing and structural variant analysis. [PDF]

BMC Genomics
Devonshire AS, Morata J, Jubin C, Abreu Pereira RP, Hernandez-Hernandez L, Yener D, Cabannes E, McGinn S, Delepine M, Fund C, Tonda R, Heath S, Dabad M, Gutierrez-Cuesta J, Sanchez Escudero I, Frias-Lopez MC, Cowen S, Whale A, Voss T, Deleuze JF, Gut I, Gut M, Foy CA.   +22 more
europepmc   +1 more source

Cellular background level of 8-oxo-7,8-dihydro-2'-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up [PDF]

, 2002
Jean‐Luc Ravanat, Thierry Douki, Pierre Duez, E. Gremaud, Karl E. Herbert, Tim Hofer, L. Lasserre, Christine Saint‐Pierre, Alain Favier, Jean Cadet   +9 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Combination of Sample Preservation Approaches and DNA Extraction Methods for Long-Read Sequencing of Nudibranchs' Genomes. [PDF]

Ecol Evol
Alberola-Mora I, Guerra-Font O, Espinoza-Calderón OD, Galià-Camps C, Džunková M.   +4 more
europepmc   +1 more source

New Method for the Extraction of DNA from White Blood Cells for the Detection of Common Genetic Variants Associated with Thrombophilia [PDF]

, 2002
Antonio Angelini, Concetta Di Febbo, Agnese Rullo, Carmine Di Ilio, Franco Cuccurullo, Ettore Porreca   +5 more
openalex   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Impact of DNA Extraction and 16S rRNA Gene Amplification Strategy on Microbiota Profiling of Faecal Samples. [PDF]

Int J Mol Sci
Toto F, Scanu M, Gramegna M, Putignani L, Del Chierico F.   +4 more
europepmc   +1 more source

Gut Microbiota Analysis Results Are Highly Dependent on the 16S rRNA Gene Target Region, Whereas the Impact of DNA Extraction Is Minor.

Journal of Biomolecular Techniques, 2017
Anniina Rintala, S. Pietilä, E. Munukka, E. Eerola, J. Pursiheimo, A. Laiho, S. Pekkala, P. Huovinen   +7 more
semanticscholar   +1 more source

Use of Magnetic Beads for Plasma Cell-free DNA Extraction: Toward Automation of Plasma DNA Analysis for Molecular Diagnostics [PDF]

, 2003
Christine Stemmer, Michèle Beau‐Faller, Erwan Pencreach, Éric Guérin, Anne Schneider, Didier Jaqmin, Elizabeth Quoix, Marie‐Pierre Gaub, P Oudet   +8 more
openalex   +1 more source