Results 261 to 270 of about 4,748,303 (367)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

One-Pot Colorimetric Nucleic Acid Test Mediated by Silver Nanoparticles for DNA Extraction and Detection. [PDF]

Biosensors (Basel)
Park SK, Trinh KTL, Lee NY.
europepmc   +1 more source

Echinococcus granulosus: DNA Extraction from Germinal Layers Allows Strain Determination in Fertile and Nonfertile Hydatid Cysts

, 2000
Laura Kamenetzky, Sergio G. Canova, Eduardo Guarnera, Mara Cecília Rosenzvit   +3 more
openalex   +1 more source

New Method for the Extraction of DNA from White Blood Cells for the Detection of Common Genetic Variants Associated with Thrombophilia [PDF]

, 2002
Antonio Angelini, Concetta Di Febbo, Agnese Rullo, Carmine Di Ilio, Franco Cuccurullo, Ettore Porreca   +5 more
openalex   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Comparing the effectiveness of different DNA extraction methods in MX-80 bentonite. [PDF]

Environ Microbiol Rep
Mijnendonckx K, Smolders C, Bartak D, Le Duc T, Morales-Hidalgo M, Povedano-Priego C, Jroundi F, Merroun ML, Leys N, Cerna K.   +9 more
europepmc   +1 more source

Extraction of plasmid DNA using reactor scale alkaline lysis and selective precipitation for scalable transient transfection.

, 2001
Jason Wright, Martin Jordan, Florian Μ. Wurm   +2 more
openalex   +2 more sources

CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability

Molecular Oncology, EarlyView.
Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki, Rose L. Jady‐Clark, Eileen E. Parkes   +2 more
wiley   +1 more source

A cost-effective and scalable approach for DNA extraction from FFPE tissues. [PDF]

Biol Methods Protoc
Geisenberger C, Chimal E, Jurmeister P, Klauschen F.   +3 more
europepmc   +1 more source

Cellular background level of 8-oxo-7,8-dihydro-2'-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up [PDF]

, 2002
Jean‐Luc Ravanat, Thierry Douki, Pierre Duez, E. Gremaud, Karl E. Herbert, Tim Hofer, L. Lasserre, Christine Saint‐Pierre, Alain Favier, Jean Cadet   +9 more
openalex   +1 more source