The cochaperone BAG3 promotes the stabilization of p53 under heat stress conditions
Under heat stress, BAG3 translocates to the nucleus and forms a complex with Hsp70 and p53, thereby promoting p53 stabilization and enhancing its transcriptional activity. These findings suggest that BAG3 functions as a cochaperone that supports p53‐mediated stress responses in cooperation with Hsp70.
Ngoc Nguyen Thi Minh+2 more
wiley +1 more source
A Colorimetric LAMP Assay for Salmonella spp. Detection: Towards a DNA Extraction-Free Approach for Pathogen Screening. [PDF]
Skenndri S+6 more
europepmc +1 more source
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma+10 more
wiley +1 more source
Comparison of Fecal DNA Extraction Kits for the Giant Panda (<i>Ailuropoda melanoleuca</i>) by Short Tandem Repeat Genotype Analysis. [PDF]
Gao J+11 more
europepmc +1 more source
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu+6 more
wiley +1 more source
An optimized CTAB method for genomic DNA extraction from green seaweeds (Ulvophyceae). [PDF]
Hossen R+5 more
europepmc +1 more source
Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda+7 more
wiley +1 more source
Optimizing fungal DNA extraction and purification for Oxford Nanopore untargeted shotgun metagenomic sequencing from simulated hemoculture specimens. [PDF]
Langsiri N+8 more
europepmc +1 more source
Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior+5 more
wiley +1 more source