Results 311 to 320 of about 2,239,481 (376)

Pathway‐level mutational signatures predict breast cancer outcomes and reveal therapeutic targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose In order to significantly improve the therapeutic treatment of breast cancer, the exploration of underlying genetic and molecular differences is absolutely necessary. Here, our goal was to integrate mutational status of entire pathways to reveal molecular pathway interactions determining survival. Experimental Approach A
Máté Posta, Balázs Győrffy
wiley   +1 more source

The BioColour Library

open access: yesColoration Technology, EarlyView.
Abstract The attraction of adopting natural and bio‐based colourants in applications has grown, but their use suffers from a lack of certification bodies, standards and reference data. In the BioColour project, we are developing an open database and tools for the characterisation, authentication and quality analysis of biocolourant sources ...
Joni Hyttinen   +2 more
wiley   +1 more source

Blood group O expression in normal tissues and tumors

open access: yesThe FEBS Journal, EarlyView.
The H antigen (O blood group), the precursor to A and B blood groups, is expressed on human erythrocytes. Two novel monoclonal antibodies generated using sea lamprey immunization, Tn4‐31L and OmcFL3‐02, specifically detect the H antigen on glycan microarrays, glycoproteins, and human cells.
Ea Kristine Clarisse Tulin   +11 more
wiley   +1 more source

Molecular epidemiology of infectious diseases: a case for increased surveillance

open access: yesBulletin of the World Health Organization
Seyed E. Hasnain
doaj   +1 more source

Lysine demethylase 4A is a centrosome‐associated protein required for centrosome integrity and genomic stability

open access: yesThe FEBS Journal, EarlyView.
KDM4A, a chromatin eraser, localizes to the centrosomes. Its demethylase activity is essential for maintaining centrosome number and integrity, independent of gene expression changes. Loss of KDM4A leads to centrosome amplification, pseudo‐bipolar spindle formation, and chromosome segregation errors, including micronuclei and chromatin bridges.
Pratim Chowdhury   +16 more
wiley   +1 more source

Structural characterisation of nucleotide sugar short‐chain dehydrogenases/reductases from the thermophilic pseudomurein‐containing methanogen Methanothermobacter thermautotrophicus ΔH

open access: yesThe FEBS Journal, EarlyView.
Nucleotide sugar short‐chain dehydrogenases/reductases (NS‐SDRs) are involved in pseudomurein and capsular polysaccharide formation in methanogenic Archaea. Methanothermobacter thermautotrophicus possesses several NS‐SDRs labelled Mth375, Mth380, Mth373, Mth631 and Mth1789.
Vincenzo Carbone   +4 more
wiley   +1 more source

Unexpected diversity of alternative reproductive tactics revealed in Water Rails (Rallus aquaticus)

open access: yesIbis, EarlyView.
Monogamy in birds was long considered a general mating system until molecular studies provided evidence of alternative reproductive strategies (ARS), which are now assumed to be present in ~90% of bird species. These ARS or tactics (ART), as we consider them in this study, include extra‐pair copulation, which can lead to extra‐pair paternity or extra ...
Alexandru Nicolae Stermin   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy