Results 121 to 130 of about 18,298 (211)

The Size, Demography, and Distribution of Cambodia's Largest Elephant Population Revealed Using Traditional Genetic Tools and a Novel SNP Panel

Integrative Zoology, EarlyView.
Asian elephant population parameters were assessed using microsatellite, SNP, and sex determination DNA markers. This represents one of the first studies in mainland Asia to demonstrate that integrating microsatellite and SNP data enhances genotyping success from degraded fecal samples, increases the number of useable samples and markers, and ...
Rachel Crouthers, Wayne Linklater, Peter Ritchie, Visattha In, Chanrith Phoeurk, Alexander Ball   +5 more
wiley   +1 more source

Quorum sensing regulators AphA and HapR differentially regulate fluvibactin biosynthesis in <i>Vibrio fluvialis</i>. [PDF]

Front Microbiol
Cheng Q, Han Y, Wang K, Ji S, Li X, Qin A, Xiao Y, Liang W, Kan B.   +8 more
europepmc   +1 more source

Mapping Allergen B‐ and T‐Cell Epitopes: Technological Advances and Their Role in Precision Allergy Therapy

Allergy, EarlyView.
ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche, Josefine Corneliussen, Kristoffer H. Johansen, Alexandre Ruiz‐Carrasco, Caroline Paulsen, Yuchen Li, Carolina Barra, Sandhya Bangaru, Monica L. Fernández‐Quintero, Ewa Bartko, Lars Blom, Esperanza Rivera‐de‐Torre   +11 more
wiley   +1 more source

Recommendations and considerations for hydroxyl radical protein footprinting-mass spectrometry. [PDF]

Nat Methods
Wecksler AT, Wang L, Bernstein LJ, Huang RY, Gupta S, Kristensen LG, Ralston CY, Sobott F, Sun Y, Brenowitz M, Farquhar ER, Chance MR, Kuang XC, Gross ML, Jones LM, Novak P, Misra SK, Sharp JS.   +17 more
europepmc   +1 more source

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

Andrology, EarlyView.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda, Jiřina Havránková, Hedvika Řimnáčová, Jiří Moravec, František Liška, Martin Knytl, Milena Králíčková, Jan Nevoral   +7 more
wiley   +1 more source

Improvement of a phylogenetic footprinting method for transcription factor binding sites recognition based on the use of bootstrap trials for the analysis of large bacterial genomic data. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Mukhin AM, Khlebodarova TM, Oshchepkov DY.   +2 more
europepmc   +1 more source

From Tumour to Bloodstream: Advancing PD‐L1 Testing With Liquid Biopsies in Non‐Small Cell Lung Cancer

Cytopathology, EarlyView.
This review explores liquid biopsy as a complementary approach to tissue‐based PD‐L1 assessment in advanced NSCLC treated with immune checkpoint inhibitors. Focusing on circulating tumour cells, extracellular vesicles, and circulating tumour DNA, it summarises current evidence, technical challenges, and future perspectives for personalised ...
R. Leporati, V. Callegari, A. Ancora, M. Palmieri, B. Riccò, E. Cabitza, L. Trudu, K. Di Emidio, C. Chiavelli, A. Eccher, I. Mastrolia, V. Catani, S. Bettelli, G. Guaitoli, M. Dominici, F. Bertolini   +15 more
wiley   +1 more source

H2‐dependent modulation of tetrahydromethanopterin S‐methyltransferase (Mtr complex) activity by the small protein MtrR in Methanosarcina mazei

The FEBS Journal, EarlyView.
Small protein MtrR is a regulator of the Mtr methyltransferase complex in Methanosarcina mazei. It binds specifically to the MtrA subunit and modulates Mtr activity in response to hydrogen (H2) availability. Deleting mtrR impairs growth in the presence but not absence of H2, indicating its role in directing methyl transfer toward an energy‐conserving ...
Tim Habenicht, Bjarne Hastedt, Liam Cassidy, Claudia Kießling, Andreas Tholey, Jan M. Schuller, Ruth A. Schmitz   +6 more
wiley   +1 more source

Global regulation and virulence mediated by the histidine-responsive local transcription factor HutC in <i>Pseudomonas aeruginosa</i>. [PDF]

mBio
Jayan KS, Naren N, Liu Y, Liu X, Luan C, Zhang X-X.   +5 more
europepmc   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source