Results 211 to 220 of about 38,912 (254)

Multimodal antibacterial potency of newly designed and synthesized Schiff's/Mannich based coumarin derivatives: potential inhibitors of bacterial DNA gyrase and biofilm production. [PDF]

RSC Adv
Pakeeraiah K, Swain PP, Sahoo A, Panda PK, Mahapatra M, Mal S, Sahoo RK, Sahu PK, Paidesetty SK.   +8 more
europepmc   +1 more source

Cloning and characterization of a DNA gyrase A gene from Escherichia coli that confers clinical resistance to 4-quinolones

, 1989
Martin E. Cullen, Anne W. Wyke, Reiko Kuroda, L. Mark Fisher   +3 more
openalex   +2 more sources

New quinazolin-2,4-dione derivatives incorporating acylthiourea, pyrazole and/or oxazole moieties as antibacterial agents via DNA gyrase inhibition. [PDF]

RSC Adv
Ibrahim AOA, Hassan A, Mosallam AM, Khodairy A, Rashdan HRM, Abdelmonsef AH.   +5 more
europepmc   +1 more source

Norfloxacin‐induced DNA gyrase cleavage complexes block Escherichia coli replication forks, causing double‐stranded breaks in vivo

, 2005
Jennifer Reineke Pohlhaus, Kenneth N. Kreuzer   +1 more
openalex   +2 more sources

Improved N-phenylpyrrolamide inhibitors of DNA gyrase as antibacterial agents for high-priority bacterial strains

Nace Zidar, Alessia Onali, Peter Peršolja, Davide Benedetto Tiz, Jaka Dernovšek, Žiga Skok, Martina Durcik, Andrej Emanuel Cotman, Martina Hrast Rambaher, Cristina D. Cruz, Päivi Tammela, Lidija Šenerović, Milija Jovanovic, Petra Szili, Márton Simon Czikkely, Csaba Pál, Anamarija Zega, Lucíja Peterlin Mašič, Janez Ilaš, Tihomir Tomašič, D. Kikelj   +20 more
openalex   +1 more source

Design, synthesis and antibacterial properties of pyrimido[4,5-b]indol-8-amine inhibitors of DNA gyrase

, 2018
David McGarry, Ian R. Cooper, Rolf Walker, Catherine E. Warrilow, Mark Pichowicz, Andrew J. Ratcliffe, Anne‐Marie Salisbury, Victoria J. Savage, Emmanuel Moyo, John Maclean, Andrew Smith, Cédric Charrier, Neil R. Stokes, David M. Lindsay, William J. Kerr   +14 more
openalex   +2 more sources

SimC7 Is a Novel NAD(P)H-Dependent Ketoreductase Essential for the Antibiotic Activity of the DNA Gyrase Inhibitor Simocyclinone

, 2015
M. Schäfer, Tung B. K. Le, S.J. Hearnshaw, Anthony Maxwell, Gregory L. Challis, Barrie Wilkinson, Mark J. Buttner   +6 more
openalex   +1 more source

Benzothiazole DNA gyrase inhibitors and their conjugates with siderophore mimics: design, synthesis and evaluation. [PDF]

RSC Adv
Durcik M, Cruz CD, Scorciapino MA, Ilaš J, Tammela P, Ceccarelli M, Mašič LP, Tomašič T.   +7 more
europepmc   +1 more source

Antibacterial efficacy and bioisosteric optimization of lead compounds from tithonia diversifolia targeting DNA gyrase B in multidrug-resistant bacteria

Olumide Oluyele, Glory Oyindamola Ejigbo, Damilola S. Bodun   +2 more
openalex   +1 more source

Microwave-assisted synthesis and in vitro and in silico studies of pyrano[3,2-c]quinoline-3-carboxylates as dual acting anti-cancer and anti-microbial agents and potential topoisomerase II and DNA-gyrase inhibitors. [PDF]

RSC Adv
Aly AA, Abd El-Naby HA, Ahmed EK, Gedamy SA, Rissanen K, Nieger M, Brown AB, Shehat MG, Shaaban MM, Atta A.   +9 more
europepmc   +1 more source