Results 161 to 170 of about 350,926 (202)
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Ligation of DNA with T4 DNA Ligase
2003Since they are involved in such important processes as DNA replication, DNA repair, and DNA recombination, DNA ligases can be found in all living cells. Two prokaryotic DNA ligases have become indispensible tools in the fields of in vitro DNA recombination and DNA synthesis. DNA ligase from E. coli is a polypeptide with a molecular weight of 74,000 and
W, Gaastra, K, Hansen
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1982
Publisher Summary DNA ligases refer to enzymes that catalyze the formation of a phosphodiester linkage between DNA chains. DNA ligases are essential reagents in studies on nucleic acid structure and metabolism. Their value derives from the specificity of the reaction and their ability to join polynucleotide chains covalently.
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Publisher Summary DNA ligases refer to enzymes that catalyze the formation of a phosphodiester linkage between DNA chains. DNA ligases are essential reagents in studies on nucleic acid structure and metabolism. Their value derives from the specificity of the reaction and their ability to join polynucleotide chains covalently.
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Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions
Ca-A Cancer Journal for Clinicians, 2021Michael L Cheng +2 more
exaly
Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
exaly
Eukaryotic DNA Ligases and DNA Repair
1998The correct joining of appropriate DNA ends is a fundamental step in many important reactions within the cell and a number of enzymes have been identified which perform these end-joining reactions. Some enzymes execute a ligation step as an intermediate of their overall reaction mechanism; DNA topoisomerases are a prime example of this type of activity
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Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids
Nature Reviews Molecular Cell Biology, 2022Eva Petermann, Li Lan, Lee Zou
exaly
The Progressing Clinical Utility of DNA Microarrays
Ca-A Cancer Journal for Clinicians, 2002Jill A Macoska
exaly