Results 191 to 200 of about 337,826 (349)

Fluorescence-, isotope- or biotin-labeling of the 5'-end of single-stranded DNA/RNA using T4 RNA ligase [PDF]

, 1997
Yohei Kinoshita, Koichi Nishigaki, Yuzuru Husimi   +2 more
openalex   +1 more source

Anti‐Inflammatory Mechanisms of Selenium Nanosheets in Ulcerative Colitis: Protein Corona, GP130 Interaction, and Transcriptomic Profile

Advanced Science, EarlyView.
SeNSs provide a biocompatible, anti‐inflammatory UC therapy. SeNSs form protein coronas enriched with AKT/PI3K/NF‐κB pathway proteins, suppress GP130 via hydrophobic interactions, and inhibit pro‐inflammatory cytokines. In DSS‐induced UC mice, SeNSs reduce inflammation, tissue damage, and disease activity by modulating cytokine, chemokine, and ...
Dingyi Shen, Li Gong, Wei Yang, Jiaqi Luo, Zhen Jin, Youzhi Tang   +5 more
wiley   +1 more source

DNA ligase IV dificiency with elevated serum IgG levels suspected to have myelodysplastic syndrome: a case report. [PDF]

BMC Pediatr, 2022
Huang M, Dong G, Lu X, Xiao F, Zhou Q, Zhang S.   +5 more
europepmc   +1 more source

Domain structure of vaccinia DNA ligase [PDF]

, 1997
JoAnn Sekiguchi, S. Shuman
openalex   +1 more source

Nanomedicine‐Driven Modulation of Reductive Stress for Cancer Therapy

Advanced Science, EarlyView.
This article introduces a novel therapeutic paradigm that deliberately induces reductive stress within tumor cells to exploit their unique biochemical vulnerabilities. It systematically reviews the underlying biological mechanisms, current detection and monitoring techniques, and emerging advanced nanotechnology platforms specifically designed to ...
Yumin Mao, Xianping Liu, Xu Chu, Feixiang Chen, Ruicheng Shi, Zonghao Liu, Yelin Wu, Yanyan Liu, Wenbo Bu   +8 more
wiley   +1 more source

Identification of Novel Inhibitors of Escherichia coli DNA Ligase (LigA). [PDF]

Molecules, 2021
Alomari A, Gowland R, Southwood C, Barrow J, Bentley Z, Calvin-Nelson J, Kaminski A, LeFevre M, Callaghan AJ, Vincent HA, Gowers DM.   +10 more
europepmc   +1 more source

Two Distinct DNA Ligase Activities in Mitotic Extracts of the Yeast Saccharomyces Cerevisiae [PDF]

, 1997
William Ramos, Nancy J. Tappe, J. Talamantez, E C Friedberg, A. E. Tomkinson   +4 more
openalex   +1 more source

A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing

Advanced Science, EarlyView.
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang, Zhengshuo Li, Run Zheng, Xiang Zheng, Jia Wang, Can Liu, Yangge Wu, Yuqing Wen, Chunlin Ou, Songqing Fan, Chenxiao Xu, Junrui Tian, Qun Yan, Hao Nan, Xiaodong Xu, Hui Wang, Qiu Peng, Jian Ma   +17 more
wiley   +1 more source

Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. [PDF]

Structure, 2022
Sverzhinsky A, Tomkinson AE, Pascal JM.
europepmc   +1 more source

Crystal Structure of Eukaryotic DNA Ligase–Adenylate Illuminates the Mechanism of Nick Sensing and Strand Joining [PDF]

, 2000
Mark Odell, Verl Sriskanda, Stewart Shuman, Dimitar B. Nikolov   +3 more
openalex   +1 more source