Results 201 to 210 of about 3,407,466 (313)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Atlantic-wide connectivity of Ascension Island green turtles revealed by finer-scale mitochondrial DNA markers. [PDF]

Conserv Genet
Coveney SA, Jiménez-Guri E, Ball S, Mianseko N, Broderick AC, Godley BJ, Hancock JM, Pereira WQ, Regalla A, Rocha RG, Senhoury C, de Thoisy B, Tilley D, Vargas SM, Weber SB, Patrício AR.   +15 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Development of DNA markers for assisted selection of cassava resistant to cassava mosaic disease (CMD). [PDF]

Breed Sci
Tokunaga H, Nhan PT, Huong PT, Anh NH, Huong LTM, Hoa TM, Trang NTH, Tung NB, Thuy CTL, Zhang X, Seki M, Ham LH.   +11 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Dataset of chloroplast intergenic spacer sequences and candidate DNA markers for species identification in <i>Hoya</i> (Apocynaceae) based on the plastome of <i>Hoya lockii</i> V.T. Pham & Aver. from Vietnam. [PDF]

Data Brief
Yongsa M, Nguyen NTT, Nguyen LTN, Sy TD, Tu TQ, Chu MH.   +5 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

The Use of DNA Markers in Rice Breeding for Blast Resistance and Submergence Tolerance as a Weed Control Factor. [PDF]

Plants (Basel)
Dubina E, Kostylev P, Makukha Y, Ruban M.   +3 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Screening and Application of DNA Markers for Novel Quality Consistency Evaluation in <i>Panax ginseng</i>. [PDF]

Int J Mol Sci
Cai S, Liao X, Xi Y, Chu Y, Liu S, Su H, Dou D, Xu J, Xiao S.   +8 more
europepmc   +1 more source