Results 191 to 200 of about 5,610,569 (399)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Methylated DNA Markers for Sporadic Colorectal and Endometrial Cancer Are Strongly Associated with Lynch Syndrome Cancers. [PDF]

open access: yesCancer Prev Res (Phila), 2023
Bramblet RM   +14 more
europepmc   +1 more source

Tumor origin detection with tissue‐specific miRNA and DNA methylation markers

open access: yesBioinform., 2018
Wei Tang   +4 more
semanticscholar   +1 more source

CODEX multiplexed tissue imaging with DNA-conjugated antibodies

open access: yesNature Protocols, 2021
Sarah Black   +8 more
semanticscholar   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Conservation of fine-scale DNA marker order in the genomes of rice and the Triticeae

open access: green, 1995
Roy P. Dunford   +5 more
openalex   +2 more sources

DNA methylation markers for diagnosis and prognosis of common cancers

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
Xiaoke Hao   +27 more
semanticscholar   +1 more source

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