Results 61 to 70 of about 3,407,466 (313)

Unveiling Plant Genetic Diversity: A Review of DNA Marker Techniques

Journal of Agricultural Sciences
DNA markers are essential tools for exploring genetic diversity and understanding population structure within plant species. These markers provide valuable insights into plant adaptation to environmental challenges and aid in uncovering genetic ...
Thana Khan
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Special features of RAD Sequencing data:implications for genotyping [PDF]

, 2012
Restriction site-associated DNA Sequencing (RAD-Seq) is an economical and efficient method for SNP discovery and genotyping. As with other sequencing-by-synthesis methods, RAD-Seq produces stochastic count data and requires sensitive analysis to develop ...
Fuentes-Utrilla, Pablo, Blaxter, Mark L, Pablo Fuentes-utrilla, Karim Gharbi, Davey, John W, Cezard, Timothée, John W. Davey, Gharbi, Karim, Pablo Fuentes‐Utrilla, Cathlene Eland, Timothée Cezard, Mark L. Blaxter, Eland, Cathlene   +12 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Continuing Fragmentation of a Widespread Species by Geographical Barriers as Initial Step in a Land Snail Radiation on Crete [PDF]

, 2013
Sauer J, Oldeland J, Hausdorf B. Continuing Fragmentation of a Widespread Species by Geographical Barriers as Initial Step in a Land Snail Radiation on Crete. PLoS ONE.
Jens Oldel, Sauer Jan, Jens Oldeland, Hausdorf Bernhard, Jan Sauer, Oldeland Jens, Sauer, Jan, Hausdorf, Bernhard, Oldeland, Jens, Bernhard Hausdorf, Jan Sauer (408909), Bernhard Hausdorf (277904), Jens Oldeland (226793)   +12 more
core   +2 more sources

Molecular and Population Genetics Tools for Farm Animal Genetic Resources Conservation: Brief Overview

Scientific Papers Animal Science and Biotechnologies, 2023
Advances in animal genome data and in genetic analysis, next to the increasing use of artificial reproductive technology resulted in progress into the animal sciences area, transposing the applied technologies into the omics field.
Claudia Terezia Socol, Lelior Iacob, Ioan Mihalca, Florin Leontin Criste   +3 more
doaj  

The assignment success for 22 horse breeds registered in the Czech Republic: The machine learning perspective

Czech Journal of Animal Science, 2021
The paper demonstrates the dependability of assignment testing in the identification of an appropriate breed to monitor comprehensive genetic information from molecular markers to analyse the collection of real population data covering 22 horse breeds ...
Lenka Štohlová Putnová, Radek Štohl
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Nomenclatural standards and genetic passports of potato cultivars bred in the A.G. Lorkh All-Russian Research Institute of Potato Farming

Биотехнология и селекция растений, 2020
In order to preserve the genetic diversity of cultivars, it is recommended to develop documentation approaches through the registration of cultivar nomenclatural standards in accordance with the International Code of Nomenclature for Cultivated Plants ...
D. А. Rybakov, O. Yu. Аntonova, I. G. Chukhina, N. А. Fomina, N. S. Klimenko, V. V. Zheltova, А. А. Meleshin, E. Z. Kochieva, E. V. Oves, Kh. Kh. Аpshev, E. А. Simakov, T. А. Gavrilenko   +11 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source