Results 11 to 20 of about 382,011 (287)
Genetic and DNA methylation changes in cotton (Gossypium) genotypes and tissues. [PDF]
PLoS ONE, 2014 In plants, epigenetic regulation is important in normal development and in modulating some agronomic traits. The potential contribution of DNA methylation mediated gene regulation to phenotypic diversity and development in cotton was investigated between
Kenji Osabe +7 more
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The Role of Host Cell DNA Methylation in the Immune Response to Bacterial Infection
Frontiers in Immunology, 2021 Host cells undergo complex transcriptional reprogramming upon infection. Epigenetic changes play a key role in the immune response to bacteria, among which DNA modifications that include methylation have received much attention in recent years.
Wanhai Qin +4 more
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DNA methylation methods: Global DNA methylation and methylomic analyses
Methods, 2021 DNA methylation provides a pivotal layer of epigenetic regulation in eukaryotes that has significant involvement for numerous biological processes in health and disease. The function of methylation of cytosine bases in DNA was originally proposed as a "silencing" epigenetic marker and focused on promoter regions of genes for decades.
Shizhao, Li, Trygve O, Tollefsbol
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DNA methylation and DNA methyltransferases [PDF]
Epigenetics & Chromatin, 2017 The prevailing views as to the form, function, and regulation of genomic methylation patterns have their origin many years in the past, at a time when the structure of the mammalian genome was only dimly perceived, when the number of protein-encoding mammalian genes was believed to be at least five times greater than the actual number, and when it was ...
John R. Edwards +3 more
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Swiss Medical Weekly, 2013 DNA methylation, the addition of a methyl group to cytosines and adenosines, regulates gene expression on a level that is usually referred to as epigenetic, that is, stably maintained during cell divisions. In humans, aberrant DNA methylation is associated with several malignancies, including cancer and so-called imprinting disorders, making it an ...
Thomas von Känel, Andreas R Huber
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Genome-wide profiling of DNA methylation and gene expression in Crassostrea gigas male gametes
Frontiers in Physiology, 2014 DNA methylation patterns and functions are variable across invertebrate taxa. In order to provide a better understanding of DNA methylation in the Pacific oyster (Crassostrea gigas), we characterized the genome-wide DNA methylation profile in male gamete
Claire E. Olson, Steven B. Roberts
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Apoptosis and DNA Methylation [PDF]
Cancers, 2011 Epigenetic mechanisms assist in maintaining gene expression patterns and cellular properties in developing and adult tissues. The molecular pathology of disease states frequently includes perturbation of DNA and histone methylation patterns, which can activate apoptotic pathways associated with maintenance of genome integrity.
Meng, Huan X +8 more
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Evaluation of the usefulness of saliva for DNA methylation analysis in cohort studies
Neuropsychopharmacology Reports, 2019 Introduction Epigenetic information such as DNA methylation is a useful biomarker that reflects complex gene‐environmental interaction. Peripheral tissues such as blood and saliva are commonly collected as the source of genomic DNA in cohort studies ...
Yui Murata +10 more
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Frontiers in Plant Science, 2015 DNA methylation is a chromatin modification that is sometimes associated with epigenetic regulation of gene expression. As DNA methylation can be reversible at some loci, it is possible that methylation patterns may change within an organism that is ...
Steven R Eichten, Nathan M Springer
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Frontiers in Genetics, 2023 Purpose: Aging is one of the most important risk factors for a number of human diseases. Epigenetic alterations, including changes in DNA methylation patterns, have been reported to be one of the hallmarks of aging. Being a malleable process, the role of
Anshika Kaushik +4 more
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