Results 351 to 360 of about 2,729,754 (384)
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Developmental Genetics, 1989
Article de synthese sur le role dans l'expression genique differentielle de la methylation des bases de l'ADN pendant le developpement des ...
Jane M. Magill, Clint W. Magill
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Article de synthese sur le role dans l'expression genique differentielle de la methylation des bases de l'ADN pendant le developpement des ...
Jane M. Magill, Clint W. Magill
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Methylation of DNA in Prokaryotes
1993A much wider variety of biological functions of postreplicative DNA methylation is observed in prokaryotes than in eukaryotes. In eukaryotes DNA methylation is primarily a means of the control of gene expression. Many chapters of this book are devoted to various aspects of this function. In prokaryotes, DNA methylation affects such diverse phenomena as
Mario Noyer-Weidner, Thomas A. Trautner
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DNA methylation and embryogenesis
1993A large number of studies have documented the methylation patterns of individual genes and repeated sequences in different tissues of various mammalian species. This has revealed a consistent picture of DNA modification where each cell type has its characteristic pattern.
Howard Cedar, Aharon Razin
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DNA Methylation and Epigenotypes [PDF]
Biochemistry (Moscow), 2005 The science of epigenetics is the study of all those mechanisms that control the unfolding of the genetic program for development and determine the phenotypes of differentiated cells. The pattern of gene expression in each of these cells is called the epigenotype. The best known and most thoroughly studied epigenetic mechanism is DNA methylation, which
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2012
Cancer has been considered a genetic disease with a wide array of well-characterized gene mutations and chromosomal abnormalities. Of late, aberrant epigenetic modifications have been elucidated in cancer, and together with genetic alterations, they have been helpful in understanding the complex traits observed in neoplasia.
Sanjeev Khosla, Gopinathan Gokul
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Cancer has been considered a genetic disease with a wide array of well-characterized gene mutations and chromosomal abnormalities. Of late, aberrant epigenetic modifications have been elucidated in cancer, and together with genetic alterations, they have been helpful in understanding the complex traits observed in neoplasia.
Sanjeev Khosla, Gopinathan Gokul
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Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1993
5-Methylcytosine (5mC) in DNA is produced by post-synthetic modification of cytosine residues, and it occurs primarily in CpG doublets in the mammalian genome. 5mC is a mutable site, because it can undergo spontaneous deamination to thymine. There is a repair mechanism which specifically recognises G.T mispairs, and replaces thymine with cytosine ...
G.W. Grigg, Robin Holliday
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5-Methylcytosine (5mC) in DNA is produced by post-synthetic modification of cytosine residues, and it occurs primarily in CpG doublets in the mammalian genome. 5mC is a mutable site, because it can undergo spontaneous deamination to thymine. There is a repair mechanism which specifically recognises G.T mispairs, and replaces thymine with cytosine ...
G.W. Grigg, Robin Holliday
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Trends in Genetics, 1999
The methylation of CpG islands is often equated with transcriptional inactivity and there is overwhelming evidence that this is the case for islands located in gene promoters. Such methylation is probably part of a mechanism to permanently silence the activities of genes, including those on the inactive X chromosome. Not all CpG islands and methylation
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The methylation of CpG islands is often equated with transcriptional inactivity and there is overwhelming evidence that this is the case for islands located in gene promoters. Such methylation is probably part of a mechanism to permanently silence the activities of genes, including those on the inactive X chromosome. Not all CpG islands and methylation
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Human Genetics, 1983
Eukaryotic genomes contain 5-methylcytosine (5mC) as a rare base.5mC arises by postsynthetic modification of cytosine and occurs, at least in animals, predominantly in the dinucleotide CpG. The base is not distributed randomly in these genomes but conforms to a pattern. This pattern varies between taxa but appears to be inherited in a semi-conservative
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Eukaryotic genomes contain 5-methylcytosine (5mC) as a rare base.5mC arises by postsynthetic modification of cytosine and occurs, at least in animals, predominantly in the dinucleotide CpG. The base is not distributed randomly in these genomes but conforms to a pattern. This pattern varies between taxa but appears to be inherited in a semi-conservative
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Annual Review of Plant Physiology and Plant Molecular Biology, 1998
▪ Abstract  Methylation of cytosine residues in DNA provides a mechanism of gene control. There are two classes of methyltransferase in Arabidopsis; one has a carboxy-terminal methyltransferase domain fused to an amino-terminal regulatory domain and is similar to mammalian methyltransferases.
William James Peacock +3 more
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▪ Abstract  Methylation of cytosine residues in DNA provides a mechanism of gene control. There are two classes of methyltransferase in Arabidopsis; one has a carboxy-terminal methyltransferase domain fused to an amino-terminal regulatory domain and is similar to mammalian methyltransferases.
William James Peacock +3 more
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DNA methylation and epigenetics
Russian Journal of Genetics, 2006In eukaryotic cells, nuclear DNA is subject to enzymatic methylation with the formation of 5-methylcytosine residues, mostly within the CG and CNG sequences. In plants and animals this DNA methylation is species-, tissue-, and organelle-specific. It changes (decreases) with age and is regulated by hormones.
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