Results 121 to 130 of about 2,576,927 (378)

Novel Bioconjugate Materials: Synthesis, Characterization and Medical Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the bioconjugation of novel materials grouped under “biological”, “hybrid” and “synthetic” categories. Medical applications ranging from cancer therapy and diagnostics to optogenetics and tissue engineering are explored, and conjugation trends are highlighted as a general guide. The review concludes with a comparison of techniques
Ellie Martin   +6 more
wiley   +1 more source

Comparison of mRNA gene expression by RT-PCR and DNA microarray

open access: yesBioTechniques, 2004
Few studies have compared the quantification of mRNA by DNA microarray to the results obtained by reverse transcription PCR (RT-PCR). In this study, mRNA was collected from the healing femoral fracture callus of adult and juvenile rats at various times ...
Wiguins Etienne   +3 more
doaj   +1 more source

Transcriptional control of the H-NS antagonists LeuO and RcsB-BglJ in Escherichia coli [PDF]

open access: yes, 2012
The bacterial nucleoid-associated protein (NAP) H-NS is involved in the organization and compaction of the bacterial chromatin and acts as a global respressor, mainly of genes that have been acquired by horizontal gene transfer and that are related to ...
Stratmann, Thomas
core  

Engineering Extracellular Microenvironments: The Impact of Fibrous Materials on Cell Behavior

open access: yesAdvanced Healthcare Materials, EarlyView.
Fibrous structures are key elements of the native extracellular matrix and crucial for directing cell behavior. This review discusses how fiber properties such as composition, diameter, and alignment affect cell responses in 2D and 3D systems. Strategies for integrating fibrous cues into engineered tissues are highlighted, and future directions for ...
Zan Lamberger, Gregor Lang
wiley   +1 more source

Genome-wide maps of DNA-protein interactions using a yeast ORF and intergenic microarray [PDF]

open access: bronze, 1999
Vishwanath R. Iyer   +8 more
openalex   +1 more source

Independent component analysis of Alzheimer's DNA microarray gene expression data

open access: yesMolecular Neurodegeneration, 2009
BackgroundGene microarray technology is an effective tool to investigate the simultaneous activity of multiple cellular pathways from hundreds to thousands of genes. However, because data in the colossal amounts generated by DNA microarray technology are
Wei Kong   +6 more
semanticscholar   +1 more source

Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review

open access: yesAdvanced Healthcare Materials, EarlyView.
This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli   +2 more
wiley   +1 more source

Fast and Economic Microarray-Based Detection of Species-, Resistance-, and Virulence-Associated Genes in Clinical Strains of Vancomycin-Resistant Enterococci (VRE)

open access: yesSensors
Today, there is a continuous worldwide battle against antimicrobial resistance (AMR) and that includes vancomycin-resistant enterococci (VRE). Methods that can adequately and quickly detect transmission chains in outbreaks are needed to trace and manage ...
Ibukun Elizabeth Osadare   +15 more
doaj   +1 more source

Defining signal thresholds in DNA microarrays: exemplary application for invasive cancer

open access: yesBMC Genomics, 2002
Background Genome-wide or application-targeted microarrays containing a subset of genes of interest have become widely used as a research tool with the prospect of diagnostic application.
Head S   +4 more
doaj   +1 more source

PiP‐Plex: A Particle‐in‐Particle System for Multiplexed Quantification of Proteins Secreted by Single Cells

open access: yesAdvanced Materials, EarlyView.
Detecting proteins secreted by a single cell while retaining its viability remains challenging. A particles‐in‐particle (PiPs) system made by co‐encapsulating barcoded microparticles (BMPs) with a single cell inside an alginate hydrogel particle is introduced.
Félix Lussier   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy