Results 141 to 150 of about 410,424 (355)

Enhancer Extrachromosomal Circular DNA ANKRD28 Elicits Drug Resistance via POU2F2‐Mediated Transcriptional Network in Multiple Myeloma

Advanced Science, EarlyView.
Enhancer eccANKRD28‐manipulated MM cells have been demonstrated to facilitate drug resistance and promote MM progression by activating the key transcription factor, POU2F2. POU2F2 interacts with sequence‐specific eccANKRD28 as well as RUNX1 and RUNX2 motifs to form the protein complex, which activates the promoter of oncogenes (IRF4, JUNB, IKZF3, et al.
Binzhen Chen, Jia Liu, Yaoxin Zhang, Changming Shi, Di Zhu, Guoqiang Zhang, Fei Xiao, Lu Zhong, Minyue Zhang, Lai Guan Ng, Honghui Huang, Tingting Lu, Jian Hou   +12 more
wiley   +1 more source

Use of DNA microarray analysis in diagnosis of bacterial and fungal endophthalmitis

Clinical Ophthalmology, 2012
Tsutomu Sakai1, Kenichi Kohzaki1, Akira Watanabe1, Hiroshi Tsuneoka1, Mitsunobu Shimadzu21Department of Ophthalmology, Jikei University School of Medicine, 2Mitsubishi Chemical Medience Corporation, Tokyo, JapanBackground: To examine the utility of DNA ...
Sakai T, Kohzaki K, Watanabe A, Tsuneoka H, Shimadzu M   +4 more
doaj  

Identification of the Copper Regulon in Saccharomyces cerevisiae by DNA Microarrays [PDF]

, 2000
Claudia Groß, Mark Kelleher, Vishwanath R. Iyer, Patrick O. Brown, Dennis R. Winge   +4 more
openalex   +1 more source

SSRP1/SLC3A2 Axis in Arginine Transport: A New Target for Overcoming Immune Evasion and Tumor Progression in Peripheral T‐Cell Lymphoma

Advanced Science, EarlyView.
Enhanced arginine uptake is a critical feature of metabolic reprogramming in PTCL, characterized by elevated expression of the arginine transporter SLC3A2. SLC3A2‐mediated arginine uptake facilitates PTCL proliferation and survival by enhancing OXPHOS metabolism and inducing immune evasion.
Yimin Ren, Lei Fan, Ling Wang, Yanping Liu, Jie Zhang, Boya Wang, Ruize Chen, Xiao Chen, Lingyu Zhuang, Yaping Zhang, Handong Sun, Jianyong Li, Wenyu Shi, Hui Jin   +13 more
wiley   +1 more source

Gene Expression Analysis of the Streptococcus pneumoniae Competence Regulons by Use of DNA Microarrays [PDF]

, 2000
Scott N. Peterson, Robin T. Cline, Hervé Tettelin, Vasily Sharov, Donald A. Morrison   +4 more
openalex   +1 more source

Targeting PTBP3‐Mediated Alternative Splicing of COX11 Induces Cuproptosis for Inhibiting Gastric Cancer Peritoneal Metastasis

Advanced Science, EarlyView.
The splicing factor PTBP3 promotes COX11 exon skipping, allowing gastric cancer organoids to evade cuproptosis. Antisense oligonucleotide drugs targeting PTBP3‐mediated COX11 alternative splicing, in combination with copper ionophores, promote cuproptosis in organoids, thereby providing a therapeutic approach for gastric cancer peritoneal metastasis ...
Yajing Zhou, Chao Dong, Xiaochun Shen, Pengbo Wang, Tao Chen, Weikang Li, Xiaotong Sun, Peiyuan Li, Chengxiang Xu, Kaipeng Duan, Dongbao Li, Jin Zhou   +11 more
wiley   +1 more source

Dipodal Silanes Greatly Stabilize Glass Surface Functionalization for DNA Microarray Synthesis and High-Throughput Biological Assays. [PDF]

Anal Chem, 2023
Das A, Santhosh S, Giridhar M, Behr J, Michel T, Schaudy E, Ibáñez-Redín G, Lietard J, Somoza MM.   +8 more
europepmc   +1 more source

Analysis of DNA Microarrays by Non-Destructive Fluorescent Staining Using SYBR ^® Green II [PDF]

, 2000
Cristina Battaglia, Giuliana Salani, Clarissa Consolandi, Luigi Rossi Bernardi, Gianluca De Bellis   +4 more
openalex   +1 more source

Gelsolin's Protective Role in MASH through F‐Actin Regulation and P53 Degradation

Advanced Science, EarlyView.
Gelsolin (GSN) maintains liver metabolic homeostasis by promoting MDM2‐mediated P53 degradation and inhibiting F‐actin/Yes‐associated protein (YAP) overactivation. Loss of GSN impairs P53 degradation, increases lipid deposition, and enhances YAP‐driven fibrosis and inflammation in metabolic‐associated steatohepatitis.
Yiwei Lu, Tong Ji, Zhichao Ye, Jianing Yan, Chao Wang, Jiachen Chen, Ziyang Jin, Yongji Zhu, Xiujun Cai, Yifan Wang   +9 more
wiley   +1 more source

Integrating data from heterogeneous DNA microarray platforms

Journal of Integrative Bioinformatics, 2015
DNA microarrays are one of the most used technologies for gene expression measurement. However, there are several distinct microarray platforms, from different manufacturers, each with its own measurement protocol, resulting in data that can hardly be ...
Valente Eduardo, Rocha Miguel
doaj   +1 more source