Results 21 to 30 of about 424,305 (326)

Cytological and transcript analyses reveal fat and lazy persister-like bacilli in tuberculous sputum [PDF]

, 2008
As nonreplicating tubercle bacilli are tolerant to the cidal action of antibiotics and resistant to multiple stresses, identification of this persister-like population of tubercle bacilli in sputum presents exciting and tractable new opportunities to ...
Alvarez, Anna L Sherratt, Bacon, Beste, Betts, Canetti, Claire Senner, Cole, Connolly, Conway, Daniel, Daugelat, Desjardin, Dhar, Dubnau, Eisen, Fenhalls, Fleischmann, Garnier, Garton, Gomez, Gurdyal S Besra, Jason Hinds, Kalscheuer, Karakousis, Kendall, Kolter, Kumar, Kumar Rajakumar, Larsen, Levin, Mangan, Manganelli, McKinney, Michael R Barer, Mitchison, Mitchison, Monahan, Mukamolova, Munoz-Elias, Murphy, Muttucumaru, Nakagawa, Natalie J Garton, Neyrolles, Olivier Neyrolles, Paramasivan, Park, Philip D Butcher, Rachman, Rajakumar, Rebecca J Smith, Reed, Richard A Adegbola, Rohde, Schnappinger, Shi, Siegele, Simon J Waddell, Sirakova, Smeulders, Sommers, Stewart, Su-Min Lee, Talaat, Talaat, Timm, Van der Geize, Voskuil, Waddell, Waddell, Waddell, Waltermann, Wayne, Wayne, Weichart, Wilkinson, Young   +77 more
core   +4 more sources

MPDA: Microarray pooled DNA analyzer

BMC Bioinformatics, 2008
Background Microarray-based pooled DNA experiments that combine the merits of DNA pooling and gene chip technology constitute a pivotal advance in biotechnology. This new technique uses pooled DNA, thereby reducing costs associated with the typing of DNA
Diccianni Mitchell B, Yu Alice LT, Lin Chien-Hsing, Li Ling-Hui, Huang Mei-Chu, Yang Hsin-Chou, Wu Jer-Yuarn, Chen Yuan-Tsong, Fann Cathy SJ   +8 more
doaj   +1 more source

The effects of mismatches on hybridization in DNA microarrays: determination of nearest neighbor parameters [PDF]

, 2010
Quantifying interactions in DNA microarrays is of central importance for a better understanding of their functioning. Hybridization thermodynamics for nucleic acid strands in aqueous solution can be described by the so-called nearest-neighbor model ...
Bloomfield, Borer, Brown, Carlon, E. Carlon, Fiche, Fish, Fotin, Freier, Gray, Held, J. Hooyberghs, Naef, P. Van Hummelen, Peyret, Pozhitkov, SantaLucia, SantaLucia, Stoughton, Sugimoto, Vainrub, Weckx, Xia, Zhang   +23 more
core   +3 more sources

Function annotation of hepatic retinoid x receptor α based on genome-wide DNA binding and transcriptome profiling. [PDF]

, 2012
BackgroundRetinoid x receptor α (RXRα) is abundantly expressed in the liver and is essential for the function of other nuclear receptors. Using chromatin immunoprecipitation sequencing and mRNA profiling data generated from wild type and RXRα-null mouse ...
Fang, Jianwen, Fang, Yaping, He, Yuqi, Liu, Hui-Xin, Wan, Yu-Jui Yvonne, Zhan, Qi   +5 more
core   +6 more sources

SIMAGE: simulation of DNA-microarray gene expression data

BMC Bioinformatics, 2006
Background Simulation of DNA-microarray data serves at least three purposes: (i) optimizing the design of an intended DNA microarray experiment, (ii) comparing existing pre-processing and processing methods for best analysis of a given DNA microarray ...
Kuipers Oscar P, Kok Jan, Jansen Ritsert C, Albers Casper J, van Hijum Sacha AFT   +4 more
doaj   +1 more source

Maternal cell-free DNA-based screening for fetal microdeletion and the importance of careful diagnostic follow-up. [PDF]

, 2015
BackgroundNoninvasive prenatal screening (NIPS) by next-generation sequencing of cell-free DNA (cfDNA) in maternal plasma is used to screen for common aneuploidies such as trisomy 21 in high risk pregnancies.
Chu, Tianjiao, Clemens, Michelle, Peters, David G, Rajkovic, Aleksandar, Saller, Devereux N, Yatsenko, Svetlana A   +5 more
core   +2 more sources

Emergence of Methicillin-Resistant Staphylococcus aureus Belonging to Clonal Complex 15 (CC15-MRSA) in Kuwait Hospitals

Infection and Drug Resistance, 2020
Edet E Udo, Samar S Boswihi, Bindu Mathew, Bobby Noronha, Tina Verghese, Aisha Al-Jemaz, Fatma Al Saqer Department of Microbiology, Faculty of Medicine, Kuwait University, Safat, KuwaitCorrespondence: Edet E UdoDepartment of Microbiology, Faculty of ...
Udo EE, Boswihi SS, Mathew B, Noronha B, Verghese T, Al-Jemaz A, Al Saqer F   +6 more
doaj  

An analysis of the use of genomic DNA as a universal reference in two channel DNA microarrays

BMC Genomics, 2005
Background DNA microarray is an invaluable tool for gene expression explorations. In the two-dye microarray, fluorescence intensities of two samples, each labeled with a different dye, are compared after hybridization.
Kapur Vivek, Gadgil Chetan, Lian Wei, Gadgil Mugdha, Hu Wei-Shou   +4 more
doaj   +1 more source

Normalizing DNA Microarray Data [PDF]

Current Issues in Molecular Biology, 2002
DNA microarrays are a powerful tool to investigate differential gene expression for thousands of genes simultaneously. Although DNA microarrays have been widely used to understand the critical events underlying growth, development, homeostasis, behavior and the onset of disease, the management of the resulting data has received little attention ...
Bilban, Martin, Buehler, Lukas K., Head, Steven, Desoye, Gernot, Quaranta, Vito   +4 more
openaire   +2 more sources

Utilizing Machine Learning Techniques for Cancer Prediction and Classification based on Gene Expression Data

UHD Journal of Science and Technology
Cancer classification through genetic evaluation has become a hot topic among researchers. It holds the promise of delivering systematic, precise, and scientifically backed diagnoses for different types of cancer. Lately, several studies have delved into
Mariwan Mahmood Hama Aziz, Sozan Abdullah Mahmood   +1 more
doaj   +1 more source