DNA Microarrays for Identifying Fishes [PDF]
Marine Biotechnology, 2008 In many cases marine organisms and especially their diverse developmental stages are difficult to identify by morphological characters. DNA-based identification methods offer an analytically powerful addition or even an alternative. In this study, a DNA microarray has been developed to be able to investigate its potential as a tool for the ...
M. Kochzius +17 more
openaire +3 more sources
Identification of significant features in DNA microarray data [PDF]
WIREs Comp Stat, 2013, 5(4): 309-325, 2013 DNA microarrays are a relatively new technology that can simultaneously measure the expression level of thousands of genes. They have become an important tool for a wide variety of biological experiments. One of the most common goals of DNA microarray experiments is to identify genes associated with biological processes of interest.
arxiv +1 more source
Direct Detection of Drug-Resistant Hepatitis B Virus in Serum Using a Dendron-Modified Microarray
Gut and Liver, 2018 Background/AimsDirect sequencing is the gold standard for the detection of drug-resistance mutations in hepatitis B virus (HBV); however, this procedure is time-consuming, labor-intensive, and difficult to adapt to high-throughput screening.
Doo Hyun Kim +11 more
doaj +1 more source
Use of genomic DNA as an indirect reference for identifying gender-associated transcripts in morphologically identical, but chromosomally distinct, Schistosoma mansoni cercariae. [PDF]
PLoS Neglected Tropical Diseases, 2008 The use of DNA microarray technology to study global Schistosoma gene expression has led to the rapid identification of novel biological processes, pathways or associations.
Jennifer M Fitzpatrick +5 more
doaj +1 more source
Physico-chemical foundations underpinning microarray and next-generation sequencing experiments [PDF]
, 2013 Hybridization of nucleic acids on solid surfaces is a key process involved in high-throughput technologies such as microarrays and, in some cases, next-generation sequencing (NGS).
A. Buhot +70 more
core +3 more sources
Breakdown of thermodynamic equilibrium for DNA hybridization in microarrays [PDF]
Phys. Rev. E 81, 012901 (2010), 2010 Test experiments of hybridization in DNA microarrays show systematic deviations from the equilibrium isotherms. We argue that these deviations are due to the presence of a partially hybridized long-lived state, which we include in a kinetic model. Experiments confirm the model predictions for the intensity vs. free energy behavior.
arxiv +1 more source
Benzo[a]pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice [PDF]
, 2014 Background: Gene expression changes induced by carcinogens may identify differences in molecular function between target and non-target organs. Target organs for benzo[a]pyrene (BaP) carcinogenicity in mice (lung, spleen and forestomach) and three non ...
Arlt, Volker M +4 more
core +2 more sources
Defects Can Increase the Melting Temperature of DNA-Nanoparticle Assemblies [PDF]
J. Phys. Chem. B, 110 (2006) 16393-16396, 2007 DNA-gold nanoparticle assemblies have shown promise as an alternative technology to DNA microarrays for DNA detection and RNA profiling. Understanding the effect of DNA sequences on the melting temperature of the system is central to developing reliable detection technology.
arxiv +1 more source
Pathogens, 2013 The microflora in environmental water consists of a high density and diversity of bacterial species that form the foundation of the water ecosystem. Because the majority of these species cannot be cultured in vitro, a different approach is needed to ...
Norihisa Ishii +9 more
doaj +1 more source
Gene expression reliability estimation through cluster-based analysis [PDF]
, 2009 Gene expression is the fundamental control of the structure and functions of the cellular versatility and adaptability of any organisms. The measurement of gene expressions is performed on images generated by optical inspection of microarray devices ...
Benso, Alfredo +3 more
core +1 more source