Results 41 to 50 of about 1,802,261 (296)

Microarray image processing: A novel neural network framework [PDF]

, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Due to the vast success of bioengineering techniques, a series of large-scale analysis tools has been developed to discover the functional organization of ...
Zineddin, Bachar
core   +7 more sources

Optical genome mapping identifies novel ENOX2::RUNX1 t(X;21)(q26.1;q22.12) rearrangement in acute myeloid leukemia-myelodysplasia related: first case report

Molecular Cytogenetics
Background Acute myeloid leukemia-myelodysplasia related (AML-MR) is a biologically and clinically distinct subtype of AML that arises in the context of prior dysplasia. It is characterized by adverse cytogenetics and poor prognosis compared to other AML
Giby V. George, Sarmad Ali, Chauncey R. Syposs, M. Anwar Iqbal   +3 more
doaj   +1 more source

Generalization of DNA microarray dispersion properties: microarray equivalent of t-distribution

Biology Direct, 2006
Background DNA microarrays are a powerful technology that can provide a wealth of gene expression data for disease studies, drug development, and a wide scope of other investigations. Because of the large volume and inherent variability of DNA microarray
Novak Jaroslav P, Kim Seon-Young, Xu Jun, Modlich Olga, Volsky David J, Honys David, Slonczewski Joan L, Bell Douglas A, Blattner Fred R, Blumwald Eduardo, Boerma Marjan, Cosio Manuel, Gatalica Zoran, Hajduch Marian, Hidalgo Juan, McInnes Roderick R, Miller III Merrill C, Penkowa Milena, Rolph Michael S, Sottosanto Jordan, St-Arnaud Rene, Szego Michael J, Twell David, Wang Charles   +23 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

EMMA 2-A MAGE-compliant system for the collaborative analysis and integration of microarray data [PDF]

, 2009
Dondrup M, Albaum S, Griebel T, et al. EMMA 2-A MAGE-compliant system for the collaborative analysis and integration of microarray data. BMC Bioinformatics.
Jünemann, Sebastian, Kahlke, Tim, Dondrup Michael, Christiane K Kleindt, Küster, Helge, Albaum, Stefan P, Goesmann, Alexander ; https://orcid.org/, Pühler Alfred, Heiko Neuweger, Runte Kai J, Mittard-Runte Virginie, Mertens, Dominik, Mittard-Runte, Virginie, Runte, Kaj J, Kuester, Helge, Henckel, Kolja, Linke Burkhard, Albaum, Stefan ; https://orcid.org/, Albaum, Stefan P., Tauch Andreas, Tim Kahlke, Goesmann Alexander, Pühler, Alfred ; https://orcid.org/, Goesmann, Alexander, Stefan P Albaum, Burkhard Linke, Kai J Runte, Helge Küster, Tauch, Andreas, Tille, Felix, Kleindt Christiane K, Virginie Mittard-Runte, Sebastian Jünemann, Küster Helge, Kolja Henckel, Griebel, Thasso, Kleindt, Christiane K., Kleindt, Christiane Katja, Griebel Thasso, Jünemann Sebastian, Neuweger Heiko, Alfred Pühler, Dondrup, Michael, Alexander Goesmann, Henckel Kolja, Kleindt, Christiane K, Andreas Tauch, Neuweger, Heiko, Linke, Burkhard, Dominik Mertens, Pühler, Alfred, Albaum Stefan P, Tille Felix, Kahlke Tim, Michael Dondrup, Thasso Griebel, Runte, Kai J., Felix Tille, Mertens Dominik   +58 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Automated evaluation and normalization of immunohistochemistry on tissue microarrays with a DNA microarray scanner

BioTechniques, 2003
Hundreds of tissue samples may be assembled in a tissue microarray format for simultaneous immunostaining assessment of protein expression profiling. A DNA microarray two-color laser scanner was used for automated analysis of tissue microarray indirect ...
Wolfgang Haedicke, Helmut H. Popper, Charles R. Buck, Kurt Zatloukal   +3 more
doaj   +1 more source

Multi-membership gene regulation in pathway based microarray analysis [PDF]

, 2011
This article is available through the Brunel Open Access Publishing Fund. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use,
Payne, AM, Pavlidis Stelios P, Swift Stephen M, Stephen M Swift, Pavlidis, SP, Payne Annette M, Swift, SM, Annette M Payne, Stelios P Pavlidis   +8 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Selenium affects genes associated with immunity and apoptosis in in vitro follicles of ewes

Austral Journal of Veterinary Sciences
Selenium plays an important role in bodily functions. It activates immune cells such as neutrophils and immunity through T cells. However, its role in ovarian follicular gene expression has not been reported.
Leonor Miranda Jiménez, María Monserrat López Velázquez, Adrián Raymundo Quero Carrillo, Alejandrina Robledo Paz   +3 more
doaj   +1 more source