Probing Hybridization parameters from microarray experiments: nearest neighbor model and beyond [PDF]
In this article it is shown how optimized and dedicated microarray experiments can be used to study the thermodynamics of DNA hybridization for a large number of different conformations in a highly parallel fashion.
Carlon, Enrico +3 more
core +3 more sources
Background Simulation of DNA-microarray data serves at least three purposes: (i) optimizing the design of an intended DNA microarray experiment, (ii) comparing existing pre-processing and processing methods for best analysis of a given DNA microarray ...
Kuipers Oscar P +4 more
doaj +1 more source
Beating the reaction limits of biosensor sensitivity with dynamic tracking of single binding events [PDF]
The clinical need for ultrasensitive molecular analysis has motivated the development of several endpoint-assay technologies capable of single-molecule readout.
Sevenler, Derin +2 more
core +2 more sources
MPDA: Microarray pooled DNA analyzer
Background Microarray-based pooled DNA experiments that combine the merits of DNA pooling and gene chip technology constitute a pivotal advance in biotechnology. This new technique uses pooled DNA, thereby reducing costs associated with the typing of DNA
Diccianni Mitchell B +8 more
doaj +1 more source
Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. [PDF]
Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and cancer. While p53 activation is responsible for many features of DBA, the role of immune system is less defined.
Bibikova, Elena +5 more
core +2 more sources
An analysis of the use of genomic DNA as a universal reference in two channel DNA microarrays
Background DNA microarray is an invaluable tool for gene expression explorations. In the two-dye microarray, fluorescence intensities of two samples, each labeled with a different dye, are compared after hybridization.
Kapur Vivek +4 more
doaj +1 more source
Expression profiles of genes regulating dairy cow fertility: recent findings, ongoing activities and future possibilities [PDF]
Subfertility has negative effects for dairy farm profitability, animal welfare and sustainability of animal production. Increasing herd sizes and economic pressures restrict the amount of time that farmers can spend on counteractive management Genetic ...
Beerda, B. +4 more
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Edet E Udo, Samar S Boswihi, Bindu Mathew, Bobby Noronha, Tina Verghese, Aisha Al-Jemaz, Fatma Al Saqer Department of Microbiology, Faculty of Medicine, Kuwait University, Safat, KuwaitCorrespondence: Edet E UdoDepartment of Microbiology, Faculty of ...
Udo EE +6 more
doaj
Application of transcriptomics in Chinese herbal medicine studies
Transcriptomics using DNA microarray has become a practical and popular tool for herbal medicine study because of high throughput, sensitivity, accuracy, specificity, and reproducibility.
Hsin-Yi Lo +5 more
doaj +1 more source
Transcriptional changes in trichothiodystrophy cells [PDF]
Mutations in three of the genes encoding the XPB, XPD and TTDA components of transcription factor TFIIH can result in the clinical phenotype of trichothiodystrophy (TTD).
Alan Lehmann +46 more
core +2 more sources

