Results 21 to 30 of about 236,655 (258)
UHD Journal of Science and TechnologyCancer classification through genetic evaluation has become a hot topic among researchers. It holds the promise of delivering systematic, precise, and scientifically backed diagnoses for different types of cancer. Lately, several studies have delved into
Mariwan Mahmood Hama Aziz +1 more
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Application of transcriptomics in Chinese herbal medicine studies
Journal of Traditional and Complementary Medicine, 2012 Transcriptomics using DNA microarray has become a practical and popular tool for herbal medicine study because of high throughput, sensitivity, accuracy, specificity, and reproducibility.
Hsin-Yi Lo +5 more
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Microarray construction of antimicrobial resistance genes from Salmonella
浙江大学学报. 农业与生命科学版, 2006 A glass-based microarray was developed to detect 11 antimicrobial resistance genes that confer resistance to aminoglycosides, tetracyclines, sulfonamides, and chloramphenicols. DNA samples were arrayed with 220 μm diameter pins at a spacing distance 1000
MA Meng-gen +4 more
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Molecular CytogeneticsBackground Acute myeloid leukemia-myelodysplasia related (AML-MR) is a biologically and clinically distinct subtype of AML that arises in the context of prior dysplasia. It is characterized by adverse cytogenetics and poor prognosis compared to other AML
Giby V. George +3 more
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Generalization of DNA microarray dispersion properties: microarray equivalent of
Biology Direct, 2006 Background DNA microarrays are a powerful technology that can provide a wealth of gene expression data for disease studies, drug development, and a wide scope of other investigations. Because of the large volume and inherent variability of DNA microarray
Novak Jaroslav P +23 more
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
BioTechniques, 2003 Hundreds of tissue samples may be assembled in a tissue microarray format for simultaneous immunostaining assessment of protein expression profiling. A DNA microarray two-color laser scanner was used for automated analysis of tissue microarray indirect ...
Wolfgang Haedicke +3 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Detection of Multiple Human Papillomavirus Genotypes in Anal Carcinoma
Infectious Agents and Cancer, 2010 Infection with human papillomavirus (HPV) is a major risk factor for development of anal squamous cell carcinoma. Despite over 100 genotypes of the virus, HPV 16 and 18 are considered pathogenic as they are seen in the majority of cervical and anal ...
Luo Linda +5 more
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source