Results 1 to 10 of about 880 (70)
FOXO1 transcription factor not only limits the cell cycle progression but also promotes cell death as a tumor suppressor protein. Though the expression of FOXO1 is largely examined in breast cancer, the regulation of FOXO1 by miRNA is yet to be explored.
Avishek Kar +3 more
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Stimuli Responsive, Programmable DNA Nanodevices for Biomedical Applications
Of the multiple areas of applications of DNA nanotechnology, stimuli-responsive nanodevices have emerged as an elite branch of research owing to the advantages of molecular programmability of DNA structures and stimuli-responsiveness of motifs and DNA ...
Udisha Singh +7 more
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DNA Nanotechnology on Bio-Membranes
In recent years, DNA nanotechnology, including both structural and dynamic DNA nanotechnology, has emerged as a powerful tool for various analytical and biomedical applications in biological membranes [...]
Bin Zhao, Mingxu You
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The control of off-target activity is a challenge for adapting CRISPR to therapeutic use. Here the authors present CRISPECTOR, a software tool to detect, evaluate and quantify editing activity, including translocations, from NGS data.
Ido Amit +12 more
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Mechanical Design of DNA Origami in the Classroom
DNA origami (DO) nanotechnology has strong potential for applications including molecular sensing, drug delivery, and nanorobotics that rely on nanoscale structural precision and the ability to tune mechanical and dynamic properties. Given these emerging
Yuchen Wang +6 more
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Recent Advances in DNA Nanotechnology for Plasmonic Biosensor Construction
Since 2010, DNA nanotechnology has advanced rapidly, helping overcome limitations in the use of DNA solely as genetic material. DNA nanotechnology has thus helped develop a new method for the construction of biosensors.
Jeong Ah Park +4 more
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Genome editing of human cluster of differentiation 34+ (CD34+) hematopoietic stem and progenitor cells (HSPCs) holds great therapeutic potential. This study aimed to optimize on-target, ex vivo genome editing using the CRISPR-Cas9 system in CD34+ HSPCs ...
Jenny Shapiro +10 more
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Obtaining Precise Molecular Information via DNA Nanotechnology
Precise characterization of biomolecular information such as molecular structures or intermolecular interactions provides essential mechanistic insights into the understanding of biochemical processes.
Qian Tang, Da Han
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DNA Nanotechnology-Enabled Fabrication of Metal Nanomorphology
In recent decades, DNA nanotechnology has grown into a highly innovative and widely established field. DNA nanostructures have extraordinary structural programmability and can accurately organize nanoscale materials, especially in guiding the synthesis ...
Mo Xie +5 more
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Strategies to Build Hybrid Protein–DNA Nanostructures
Proteins and DNA exhibit key physical chemical properties that make them advantageous for building nanostructures with outstanding features. Both DNA and protein nanotechnology have growth notably and proved to be fertile disciplines.
Armando Hernandez-Garcia
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