Results 1 to 10 of about 6,540 (156)

Mechanical Flexibility Enables DNA Origami to Overcome Steric Confinement in Mucus. [PDF]

open access: yesAdv Sci (Weinh)
Mechanical flexibility is introduced as a design parameter to enhance nanocarrier transport in mucus. Using DNA origami, flexibility is decoupled from size, shap and surface chemistry, revealing improved passage through confined hydrogel networks. While surface passivation reduces aggregation, flexibility further boosts transport, offering a general ...
Tollemeto M   +5 more
europepmc   +3 more sources

Magnetic DNA Origami Nanorotors. [PDF]

open access: yesAdv Mater
Magnetic actuation is a powerful and broadly applicable actuation mechanism due to its programmability and compatibility with biological entities. Here we demonstrate magnetic DNA origami nanorotors (MADONAs) by assembling magnetic nanocubes on DNA origami.
Weiß LJK   +13 more
europepmc   +3 more sources

Bioproduction of ∼10 knt single-stranded DNA for constructing large DNA origami structures [PDF]

open access: yesMaterials Today Bio
DNA origami structures based on M13 scaffolds have limitations in terms of functional integration and size expansion. Using longer scaffold strands can substantially increase the number of programmable functional sites and size of DNA origami. Therefore,
Meiling Lu   +11 more
doaj   +2 more sources

The effect of long-term ambient storage on the morphology of adhered DNA origami [PDF]

open access: yesComputational and Structural Biotechnology Journal
DNA origami has the potential to fabricate nanotechnologies from nano-photonics to nano-electronics. To position this approach as a technique to replace conventional fabrication methods the stability of the structures needs to be well understood under a ...
H. McNiven, R. Seviour
doaj   +2 more sources

DNA origami-based drug delivery and cell manipulation: toward intelligent nanomedicine [PDF]

open access: yesRSC Chemical Biology
DNA origami has emerged as a versatile platform for constructing nanoscale architectures with precise shape programmability, molecular-level addressability, and dynamic structural reconfigurability.
Yuki Suzuki
doaj   +2 more sources

DNA origami technology for biomedical applications: Challenges and opportunities

open access: yesMedComm – Biomaterials and Applications, 2023
DNA origami, a promising branch of structural DNA technology, refers to the technique of folding a single‐stranded DNA scaffold into well‐defined nanostructures.
Ling Li   +4 more
doaj   +1 more source

Recent Advances of DNA Origami Technology and Its Application in Nanomaterial Preparation

open access: yesSmall Structures, 2023
In recent years, the unrivalled self‐assembly properties of DNA molecules have driven the rapid development of a new class of DNA self‐assembly technology—DNA origami technology.
Wenjing Jiang   +7 more
doaj   +1 more source

Surface Assembly of DNA Origami on a Lipid Bilayer Observed Using High-Speed Atomic Force Microscopy

open access: yesMolecules, 2022
The micrometer-scale assembly of various DNA nanostructures is one of the major challenges for further progress in DNA nanotechnology. Programmed patterns of 1D and 2D DNA origami assembly using specific DNA strands and micrometer-sized lattice assembly ...
Masayuki Endo
doaj   +1 more source

Folate-Functionalized DNA Origami for Targeted Delivery of Doxorubicin to Triple-Negative Breast Cancer

open access: yesFrontiers in Chemistry, 2021
DNA origami has emerged as a versatile platform for diverse applications, namely, photonics, electronics, (bio) sensing, smart actuator, and drug delivery.
Suchetan Pal, Tatini Rakshit
doaj   +1 more source

Direct visualization of floppy two-dimensional DNA origami using cryogenic electron microscopy

open access: yesiScience, 2022
Summary: Two-dimensional (2D) DNA origami that is capable of self-assembling into complex 2D and 3D geometries pave the way for a bottom-up synthesis for various applications in nano/biotechnology. Here, we directly visualized the aqueous structure of 2D
Heng Ni   +9 more
doaj   +1 more source

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