Results 41 to 50 of about 6,866 (163)

Exploring the Potential Mechanism of Umbilical Cord Mesenchymal Stem Cell Therapy for Chronic Atrophic Gastritis Based on Multi‐Omics Technology

Stem Cells International, Volume 2026, Issue 1, 2026.
Background Chronic atrophic gastritis (CAG), a prevalent gastrointestinal disorder, is characterized by gastric mucosal atrophy and increased cancer risk. Mesenchymal stem cells (MSCs) exhibit immunomodulatory, anti‐inflammatory, and tissue‐regenerative properties; however, their therapeutic potential for CAG remains underexplored.
Pengchao Bai, Qichao Liu, Miaomiao Yin, Yan Liu, Jianliang Sui, Saihan Wang, Ruikang Jia, Huiyun Liu, Feiyue Zhao, Alain Chapel   +9 more
wiley   +1 more source

The 3' to 5' exoribonuclease DIS3: from structure and mechanisms to biological functions and role in human disease [PDF]

, 2015
DIS3 is a conserved exoribonuclease and catalytic subunit of the exosome, a protein complex involved in the 3’ to 5’ degradation and processing of both nuclear and cytoplasmic RNA species.
Carazo-Salas, Drach, Kinoshita, Lim, Noguchi, Ohkura, Sazer, Suzuki   +7 more
core   +2 more sources

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, Volume 15, Issue 12, Page 2001-2020, December 2025.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Expanding the diversity of mycobacteriophages: Insights into genome architecture and evolution [PDF]

, 2011
Mycobacteriophages are viruses that infect mycobacterial hosts such as Mycobacterium smegmatis and Mycobacterium tuberculosis. All mycobacteriophages characterized to date are dsDNA tailed phages, and have either siphoviral or myoviral morphotypes ...
Agustin, B, Al-Atrache, Z, Alcoser, TA, Alexander, LM, Alfano, MB, Alford, ST, Amy, NE, Anderson, AG, Anderson, MD, Ang, AAS, Barber, AJ, Barker, LP, Barrett, JM, Barshop, WD, Bauerle, CM, Bayles, IM, Belfield, KL, Best, AA, Bowman, CA, Boyer, CA, Bradley, KW, Bradley, VA, Broadway, LN, Budwal, K, Busby, KN, Campbell, AM, Campbell, IW, Carey, A, Caruso, SM, Chew, RD, Cockburn, CL, Cohen, LB, Corajod, JM, Cresawn, SG, Davis, KR, Deng, L, Denver, DR, Dixon, BR, Ekram, S, Elgin, SCR, Engelsen, AE, English, BEV, Erb, ML, Estrada, C, Filliger, LZ, Findley, AM, Forbes, L, Forsyth, MH, Fox, TM, Fritz, MJ, Garcia, R, George, ZD, Georges, AE, Gissendanner, CR, Goff, S, Goldstein, R, Gordon, KC, Green, RD, Guerra, SL, Guiney-Olsen, KR, Guiza, BG, Haghighat, L, Hagopian, GV, Harmon, CJ, Harmson, JS, Hartzog, GA, Harvey, SE, He, KJ, He, S, Healy, KE, Higinbotham, ER, Hildebrandt, EN, Ho, JH, Hogan, GM, Hohenstein, VG, Holz, NA, Huang, VJ, Hufford, EL, Hynes, PM, Jackson, AS, Jacobs-Sera, D, Jansen, EC, Jarvik, J, Jasinto, PG, Jordan, TC, Kasza, T, Katelyn, MA, Kelsey, JS, Kerrigan, LA, Khaw, D, Kim, J, Knutter, JZ, Ko, CC, Larkin, GV, Laroche, JR, Latif, A, Manuel, A, Peebles, CL, Pope, WH, Russel, DA   +99 more
core   +1 more source

The Role and Therapeutic Potential of the cGAS‐STING Signaling Pathway in Alzheimer's Disease

Brain and Behavior, Volume 15, Issue 12, December 2025.
This work reveals the relationship between the cGAS‐STING signaling pathway and the pathological mechanisms of Alzheimer's disease.The role of the cGAS‐STING signaling pathway in AD pathology. AD leads to the production of neutrophil extracellular traps (NETs), endoplasmic reticulum (ER) stress, and the release of mitochondrial DNA (mtDNA) and nuclear ...
Xue Li, Wei Gao, Qiuyan Ye, Honglin Li
wiley   +1 more source

[Terminal DNA nucleotidyltransferase in blastic crisis in myelocytic leukemia].

Acta haematologica Polonica, 1982
The importance of determination of the activity of TdT is discussed in the light of a case of chronic myeloid leukaemia in a patient aged 55 years in whom after 4 years from the onset of the disease blastic crisis developed. High TdT activity was correlated with other features of blastic crisis of lymphoid character and with good response to ...
E, Rudzka, W, Bartnikowa, J, Hołowiecki, J, Japa, K, Schneiberg   +4 more
openaire   +1 more source

“Expanding the Lactococcal Cell Wall Polysaccharide Paradigm: Novel Structures and Metabolic Pathways in the Emerging Dairy Species Pseudolactococcus laudensis and Pseudolactococcus raffinolactis”

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
This study characterizes the genetic diversity of Pseudolactococcus laudensis and Pseudolactococcus raffinolactis regarding cell wall polysaccharides (CWPS) and exopolysaccharide (EPS) biosynthesis, uncovering novel genotypes and biosynthetic pathways.
Axel Soto‐Serrano, Irina Sadovskaya, Evgeny Vinogradov, Wenwen Li, Jun‐Hyeok Yu, Kelsey White, Douwe van Sinderen, Lukasz Krych, Paulina Deptula, Jennifer Mahony   +9 more
wiley   +1 more source

Nuclear Surveillance and Degradation of Hypomodified Initiator tRNA\u3csup\u3eMet\u3c/sup\u3e in \u3cem\u3eS. cerevisiae\u3c/em\u3e [PDF]

, 2004
The tRNA m1A58 methyltransferase is composed of two subunits encoded by the essential genes TRM6 and TRM61 (formerly GCD10 and GCD14). The trm6-504 mutation results in a defective m1A methyltransferase (Mtase) and a temperature-sensitive growth phenotype
Anderson, James T., Hinnebusch, Alan G., Kadaba, Sujatha, Krecic, Annette M., Krueger, Anna, Trice, Tamyra   +5 more
core   +1 more source

Prevalence and characterization of integrons in blood culture Enterobacteriaceae and gastrointestinal Escherichia coli in Norway and reporting of a novel class 1 integron-located lincosamide resistance gene [PDF]

, 2004
Background Class 1 integrons contain genetic elements for site-specific recombination, capture and mobilization of resistance genes. Studies investigating the prevalence, distribution and types of integron located resistance genes are ...
Heir, Even, Lindstedt, Bjørn-Arne, Leegaard, Truls M, Gjernes, Elisabet, Kapperud, Georg   +4 more
core   +2 more sources

Comparative Genomics of Lactococcus spp. From Global Aquaculture Outbreaks Reveals Virulence Determinants, Antibiotic Resistance, and Phage Defence Mechanisms

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Lactococcus petauri predominated in isolates from outbreaks of lactococcosis, suggesting a shift in disease aetiology. Genomic analysis revealed diverse virulence factors, prophage and resistance genes, while antimicrobial susceptibility testing showed uniform resistance to common antibiotics found in farming systems, emphasising the need for ...
Adam M. Blanchard, Bailey Secker, Robert J. Atterbury, Samantha J. Windle, Ha Thanh Dong, Janchai Wongkaew, Le Thanh Dien, David Huchzermeyer, Bernard Mudenda Hang'ombe, Saengchan Senapin   +9 more
wiley   +1 more source