Results 141 to 150 of about 1,473,978 (184)

Small molecules restore mutant mitochondrial DNA polymerase activity. [PDF]

open access: yesNature
Valenzuela S   +30 more
europepmc   +1 more source

Eukaryotic DNA Polymerases

Annual Review of Biochemistry, 2002
▪ Abstract  Any living cell is faced with the fundamental task of keeping the genome intact in order to develop in an organized manner, to function in a complex environment, to divide at the right time, and to die when it is appropriate. To achieve this goal, an efficient machinery is required to maintain the genetic information encoded in DNA during ...
Hubscher U, Maga G, Spadari S
openaire   +4 more sources

DNA‐Dependent DNA Polymerases

Current Protocols in Molecular Biology, 2008
AbstractThis unit presents characteristics and reaction conditions of the DNA‐dependent DNA polymerases, including E. coli DNA polymerase I and its Klenow fragment, T4 DNA polymerase, native and modified T7 DNA polymerase, phi29 DNA polymerase, Bst DNA polymerase, and Taq DNA polymerase. The unit also provides overviews of other classes of thermophilic
Rebecca B, Kucera, Nicole M, Nichols
openaire   +2 more sources

Reticulocyte DNA polymerase

Nature, 1974
DNA polymerase has been isolated from the cytoplasm of several mammalian tissues as well as several cell lines in culture1–8. This has been puzzling because DNA replication and repair are processes generally believed to be restricted to the nucleus, where chromatin is located.
J J, Byrnes   +3 more
openaire   +2 more sources

Eukaryotic DNA polymerases

Current Opinion in Structural Biology, 2018
The eukaryotic DNA replication machinery is conserved from yeast to humans and requires the actions of multiple DNA polymerases. In addition to replicative DNA polymerases for duplication of the leading and lagging DNA strands, another group of specialized polymerases is required for DNA repair and/or translesion DNA synthesis (TLS).
Rinku, Jain   +2 more
openaire   +2 more sources

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