Results 181 to 190 of about 542,507 (360)

The MTHFR C677T polymorphism and global DNA methylation in oral epithelial cells

open access: yesGenetics and Molecular Biology, 2013
DNA methylation is mediated by DNA methyltransferases (DNMTs) that add a methyl group to the 5'-carbon of cytosine. The enzyme methylenetetrahydrofolate reductase (MTHFR) catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5 ...
Isabela Tatiana Sales de Arruda   +2 more
doaj  

Genomic Structural Variations Provide Insights Into Litter Size and Teat Number Traits in Hu Sheep

open access: yesAnimal Research and One Health, EarlyView.
Here, we conducted whole genome sequencing on 300 Hu sheep with an average depth of 16.51X. Two candidate genes associated with litter size and teat number traits were identified, namely MAST2 and AFDN. ABSTRACT Litter size and the teat number are important economic indicators in sheep production.
Xin Xiang   +3 more
wiley   +1 more source

A Lactobacillus helveticus -Specific DNA Probe Detects Restriction Fragment Length Polymorphisms in This Species [PDF]

open access: bronze, 1992
Clara G. de los Reyes‐Gavilán   +4 more
openalex   +1 more source

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

open access: yesAnimal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu   +6 more
wiley   +1 more source

Impact of multiple genetic polymorphisms on effects of a 4-week blueberry juice intervention on ex vivo induced lymphocytic DNA damage in human volunteers [PDF]

open access: bronze, 2007
Lonneke C. Wilms   +10 more
openalex   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

open access: yesArthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Nucleosomes shape DNA polymorphism and divergence. [PDF]

open access: yesPLoS Genet, 2014
Langley SA, Karpen GH, Langley CH.
europepmc   +1 more source

Plasma Proteomics Identifies Thousand‐and‐One–Amino Acid Kinase 3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

open access: yesArthritis &Rheumatology, EarlyView.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin   +15 more
wiley   +1 more source

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