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Postradiation DNA Polymorphism
Annals of the New York Academy of Sciences, 2001Abstract: The presence of DNA molecules with tumor‐specific genetic alterations has been demonstrated in the plasma of cancer patients. Such plasma DNA fragments may be immunogenic and provide immunologic support to the malignant cells. Further, the tumor‐specific plasma DNA may participate in the adaptive processes of the tumor cells in the cancer ...
S S, Sherlina, V G, Vladimirov
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Nature New Biology, 1972
X-ray fibre diffraction shows that natural very AT-rich DNA exists in at least four novel and distinct conformations depending on the sequence and salt content.
S, Bram, P, Tougard
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X-ray fibre diffraction shows that natural very AT-rich DNA exists in at least four novel and distinct conformations depending on the sequence and salt content.
S, Bram, P, Tougard
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Structural polymorphism in DNA
Journal of Molecular Biology, 1983We have used the enzyme micrococcal nuclease and the methylating reagent dimethyl sulfate to examine the structural properties of eukaryotic DNAs. Our studies demonstrate extensive structural polymorphism in the DNA double helix. Moreover, we find that the distribution of helical variants is in some instances correlated with the functional organization
A, Udvardy, P, Schedl
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New England Journal of Medicine, 1995
One of the most important tools underlying the revolution in medical genetics is the ability to visualize sequence differences directly in DNA. When studied in the context of a population, these differences in DNA sequences are called polymorphisms; they may occur in coding regions (exons) or noncoding regions of genes.
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One of the most important tools underlying the revolution in medical genetics is the ability to visualize sequence differences directly in DNA. When studied in the context of a population, these differences in DNA sequences are called polymorphisms; they may occur in coding regions (exons) or noncoding regions of genes.
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Polymorphism of DNA double helices
Journal of Molecular Biology, 1980Abstract Native DNA duplexes in fibers exist usually in one of three well-known ( A , B and C ) forms depending on relative humidity, type of cations and the amount of retained salt. To determine the precise influence of these factors and the effect of base composition, as well as base sequence, on DNA secondary structure, X-ray diffraction ...
A G, Leslie +3 more
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Polymorphism of Human Mitochondrial DNA
Russian Journal of Genetics, 2003To date, a large data set on the mitochondrial DNA (mtDNA) sequence variation in human populations has been accumulated. The use of direct sequencing of the main noncoding region of mtDNA along with the RFLP analysis provide performance of complex analysis of mtDNA polymorphism in human populations.
M A, Bermisheva +2 more
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