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“Genetics” and DNA polymorphisms
Behavioral and Brain Sciences, 1995AbstractFour questions are raised about Mealey's genetic argument: (1) Where is the evidence that secondary sociopathy is less heritable than primary sociopathy? (2) What is the genetic correlation between the two types of sociopathy? (3) How does genotype-environment interaction relate?
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Mitochondrial DNA polymorphism in substantia nigra
Journal of the Neurological Sciences, 1996Inefficiencies in mitochondrial respiration mainly affecting complex I and IV activities, occur with increasing age and have been suggested as a possible etiological factor in age-related neurodegenerative diseases. It has been suggested that this finding may be explained by an accumulation of mtDNA mutations.
R M, Kapsa +8 more
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Mitochondrial DNA Polymorphisms
2013The analysis of genetic variation occurring in human mitochondrial DNA has characterized the field of human population genetics since this small molecule has been sequenced in 1981. First analyses were carried out by restriction analysis and they immediately suggested that mitochondrial DNA polymorphisms could allow a phylogenetic reconstruction of the
Passarino G, ROSE, Giuseppina
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DNA Polymorphisms - Practical use
1988The Home Office Forensic Science laboratories in England and Wales group blood and blood-stains in the following systems: ABO, PGM, ACP, Hp and Gc. In combination these systems provide a mean discriminating power (DP) of 0.99. For semen stains the situation is much less satisfactory, only two systems are used routinely PGM and ABO.
D J Werrett +3 more
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Conformational Polymorphism in DNA
1989Biological systems are characterized by the abundant participation of macromolecules in carrying out most of their activities. These activities are varied and include information transfer in which nucleic acids play a specialized role. The proteins form organized structures including the catalytically active molecules that are responsible for ...
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Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions
Ca-A Cancer Journal for Clinicians, 2021Michael L Cheng +2 more
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Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Manel Esteller
exaly
1976
The salts of deoxyribonucleic acid (DNA) are in many ways living molecules whose morphological characteristics are dependent on their genetic information and on their past and present environment. However, until very recently, DNA was not considered to possess variable structures — in short, it was not thought to be polymorphic.
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The salts of deoxyribonucleic acid (DNA) are in many ways living molecules whose morphological characteristics are dependent on their genetic information and on their past and present environment. However, until very recently, DNA was not considered to possess variable structures — in short, it was not thought to be polymorphic.
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Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids
Nature Reviews Molecular Cell Biology, 2022Eva Petermann, Li Lan, Lee Zou
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