Results 161 to 170 of about 3,903,497 (411)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Primer Requirement and Template Specificity of a DNA Polymerase of Chick Embryo [PDF]

, 1973
François Rougeon, Gilbert Brun, Jose Carlos da Costa Maia, François Chapeville   +3 more
openalex   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Transcription of DNA from the 70 S RNA of Rous Sarcoma Virus I. Identification of a Specific 4 S RNA Which Serves as Primer [PDF]

, 1974
J E Dahlberg, Robert C. Sawyer, John M. Taylor, Anthony J. Faras, Warren Levinson, H. M. Goodman, J. Michael Bishop   +6 more
openalex   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Culicidae-centric metabarcoding through targeted use of D2 ribosomal DNA primers. [PDF]

PeerJ, 2020
Pedro PM, Amorim J, Rojas MVR, Sá IL, Galardo AKR, Santos Neto NF, Pires de Carvalho D, Nabas Ribeiro KA, Razzolini MTP, Sallum MAM.   +9 more
europepmc   +1 more source

Transcription of DNA from the 70 S RNA of Rous Sarcoma Virus II. Structure of a 4 S RNA Primer [PDF]

, 1974
Anthony J. Faras, J E Dahlberg, Robert C. Sawyer, Fumio Harada, John M. Taylor, Warren Levinson, J. Michael Bishop, H. M. Goodman   +7 more
openalex   +1 more source

The possibility of sex identification in beluga (Huso huso) by using PCR-RAPD technique [PDF]

, 2004
The goal of this study was to find a sex-specific DNA sequences in the male and female genomes of beluga (Huso huso), by random amplified polymorphic DNA (RAPD) assays performed on pooled DNA samples.
Kalbasi, M.R., Keyvan Shokoo, S., Pourkazemi, M.   +2 more
core  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Detection of human papillomavirus DNA sequences in oral lesions using polymerase chain reaction [PDF]

, 2007
The purpose of the present study was to estimate the frequency of HPV DNA in four groups of oral lesions, including oral squamous cell carcinoma. Sixty paraffin-embedded oral tissue samples were examined for the presence of HPV DNAs using the PCR ...
Alizadeh, N., Chamani, G., Eslami, B., Hamkar, R., Kakooei, S., Mohammadalizadeh, S., Moradie, A., Zarei, M.R.   +7 more
core   +1 more source