Results 171 to 180 of about 1,454,497 (332)
Direct Primer Walking on P1 Plasmid DNA [PDF]
BioTechniques, 1997 Benes, V. +4 more
openaire +5 more sources
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
High-Throughput SNP Genotyping by SBE/SBH
, 2005 Despite much progress over the past decade, current Single Nucleotide Polymorphism (SNP) genotyping technologies still offer an insufficient degree of multiplexing when required to handle user-selected sets of SNPs.
Mandoiu, Ion I., Prajescu, Claudia
core +2 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
tRNATrp as primer for RNA-directed DNA polymerase: structural determinants of function.
, 1979 Barbara Cordell +3 more
openalex +1 more source
Fluorescence-based DNA sequencing with hexamer primers [PDF]
Nucleic Acids Research, 1993 Lloyd M. Smith, Weiying Hou
openaire +4 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
DNA Amplification Fingerprinting Using Two Long Primers
BioTechniques, 2001 Araceli Díaz-Perales +2 more
doaj +1 more source
DNA Sequencing Directly from a Mixture Using Terminal-Base-Selective Primers [PDF]
, 1994 Hideto Furuyama
openalex +1 more source