Results 181 to 190 of about 3,903,497 (411)

Subspecies of DNA polymerase α from calf thymus with different fidelity in copying synthetic template-primers [PDF]

, 1983
Sabine Brosius, Frank Große, Gerhard Krauss   +2 more
openalex   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

The elongation of mismatched primers by DNA polmerasea from α calf thymus [PDF]

, 1983
Bernd Reckmann, Frank Große, Gerhard Krauss   +2 more
openalex   +1 more source

Towards a better characterization of endogenous badnavirus sequences of yams (Dioscorea spp.) [PDF]

, 2013
Yams, and more generallytubers, are very important crops for food security in tropical and subtropical countries.They are propagated vegetativelytherefore they accumulate viruses over long periods of time.
Filloux, Denis, Iskra Caruana, Marie-Line, Laboureau, Nathalie, Muller, Emmanuelle, Pavis, Claudie, Roumagnac, Philippe, Teycheney, Pierre-Yves, Umber, Marie   +7 more
core  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Glimpse of past dynamics: A new set of phytoplankton primers for sedaDNA

Environmental DNA
Sedimentary ancient DNA (sedaDNA) offers an important opportunity for investigating long‐term community dynamics. Nevertheless, sedaDNA is challenging since DNA is degraded and fragmented over time.
Juliane Romahn, Damian Baranski, Alexandra Schmidt, Jérôme Kaiser, Helge Arz, Laura S. Epp, Anke Kremp, Miklós Bálint   +7 more
doaj   +1 more source

The algorithm of estimation of the K_m values for primers of various structure and length in the polymerization reaction catalyzed by Klenow fragment of DNA polymerase I from E.coli [PDF]

, 1989
Georgy A. Nevinsky, A.V. Nemudraya, А. С. Левина, V.V. Khomov   +3 more
openalex   +1 more source

Rapid identification of European (Anguilla anguilla) and North American eel (Anguilla rostrata) by polymerase chain reaction. [PDF]

, 2006
A rapid and cost effective DNA test is described to identify European eel (Anguilla anguilla) and North American eel (Anguilla rostrata). By means of polymerase chain reaction (PCR) technique parts of the mitochondrial cytochrome b gene are amplified ...
Trautner, Jochen
core  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Mutations affecting hepadnavirus plus-strand DNA synthesis dissociate primer cleavage from translocation and reveal the origin of linear viral DNA [PDF]

, 1991
Silvija I. Staprans, Daniel D. Loeb, Don Ganem   +2 more
openalex   +1 more source