Results 221 to 230 of about 1,480,527 (305)

A novel, minimally invasive diagnostic test for KIT exon 11 internal tandem duplications in canine cutaneous mast cell tumours I: Assay development

Evans JO, Hill LS, Beck S, Edmunds G, Dobromylskyj M, Tornillo G, Smalley MJ.   +6 more
europepmc   +1 more source

In vitro culture of human-infecting Encephalitozoon spp. for genome sequencing with minimal host contaminant. [PDF]

PLoS One
Dos Santos ACM, Liang P, Juárez OX, Pombert JF, Tuz K.   +4 more
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

A WYL transcriptional regulator activates the DNA damage response pathway in Acinetobacter species. [PDF]

Nucleic Acids Res
Ellison TJ, Smith TA, Vennapusa N, Hummels KR, Ellison CK.   +4 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Investigating the Relationship Human Parvovirus B19 Infection in Benign and Malignant Salivary Gland Tumors. [PDF]

J Dent (Shiraz)
Farhadi A, Dehghani Nazhvani A, Faghihi F, Khademi MH, Rezazadeh H.   +4 more
europepmc   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Development and Evaluation of a Dual-Target One-Step Nested PCR for the Detection of Spotted Fever Group <i>Rickettsia</i> spp. in Ticks. [PDF]

Pathogens
Foo PC, Jacob C, Mawang CI, Che Lah EF, Ahamad M.   +4 more
europepmc   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

High-throughput detection of microeukaryotic parasites in insects using Nanopore sequencing. [PDF]

Microb Genom
Bessette E, Edwards S, Williams BAP.
europepmc   +1 more source