Results 151 to 160 of about 763,201 (203)
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2003
Many research workers and clinicians working in routine laboratories are now using the "tools" developed by molecular biologists over the past 10 years to produce DNA sequences that can be used as probes to detect specific genes. Thus it is possible to screen food for salmonella (1) or other organisms in a test much more quickly than conventional ...
J L, Woodhead +3 more
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Many research workers and clinicians working in routine laboratories are now using the "tools" developed by molecular biologists over the past 10 years to produce DNA sequences that can be used as probes to detect specific genes. Thus it is possible to screen food for salmonella (1) or other organisms in a test much more quickly than conventional ...
J L, Woodhead +3 more
openaire +2 more sources
Current Biology, 1992
Current methods for DNA probe analysis in principle provide access to the total genetic information of any organism and permit applications in health care, for example. In practice, however, greatly improved efficiency of methods for decoding genetic information is required for both research and routine applications.
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Current methods for DNA probe analysis in principle provide access to the total genetic information of any organism and permit applications in health care, for example. In practice, however, greatly improved efficiency of methods for decoding genetic information is required for both research and routine applications.
openaire +2 more sources
Probing Mouse Origins with Random DNA Probes
1988Until not so long ago, many villages and towns used to have their own chroniclers who took it upon themselves to record for posterity those events which they believed to be the most important in the life of the community. They were, of course, no professionals; they were farmers, bakers, shoemakers, or pursued whatever occupation happened to be in ...
J, Klein +3 more
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JAMA, 1987
The emergence of recombinant DNA technology in the 1970s has given rise to new diagnostic techniques based on DNA probes. The Food and Drug Administration's interest in these probes stems from its regulatory responsibilities regarding DNA probes as medical devices. The agency also sees DNA probes as valuable tools in meeting its mission of identifying,
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The emergence of recombinant DNA technology in the 1970s has given rise to new diagnostic techniques based on DNA probes. The Food and Drug Administration's interest in these probes stems from its regulatory responsibilities regarding DNA probes as medical devices. The agency also sees DNA probes as valuable tools in meeting its mission of identifying,
openaire +2 more sources
DNA Methyltransferase Probing of DNA-Protein Interactions
2006Effective methods of probing chromatin structure without disrupting DNA-protein interactions and associations are necessary for creating an accurate picture of chromatin and its processes in vivo. Expression of cytidine-5 DNA methyltransferases (C5 DMTases) in Saccharomyces cerevisiae provides a powerful noninvasive method of assaying relative DNA ...
Scott A, Hoose, Michael P, Kladde
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Internal Labeling of DNA Probes
2003Ralph Rapley and BimalD.M. Theophilus, 'Internal labeling of DNA Probes' in R. Rapley and B. D. M. Theophilus, eds., PCR Mutation Detection Protocols (Totowa: Humana Press 2002) ISBN: 978-0-89603-617-8, eISBN: 978-1-59259-273-9, DOI: 10.1385/1-59259-273-2:013 © 2002 Humana Press Inc., Totowa, NJ.
Ralph, Rapley, Bimal D M, Theophilus
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Probing RNA Translocases with DNA
2014For some helicases, it is possible to investigate RNA translocase activity on DNA substrates because the enzyme acts on both substrates. Potassium permanganate (KMnO4) footprinting is a method used to chemically probe the conformation of DNA as well as the binding of proteins.
Kimberly A, Reynolds +2 more
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Probing DNA Structure With Nanoparticles
2005Semiconductor nanoparticles, also known as quantum dots, are receiving increasing attention for their biological applications. These nanomaterials are photoluminescent and are being developed both as dyes and as sensors. Here we describe our "sensor" use of quantum dots to detect different intrinsic DNA structures.
Rahina, Mahtab, Catherine J, Murphy
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DNA-Based Stable Isotope Probing
2019Microbiomes on Earth are often considered the most heterogeneous biological entities, but their vital roles in driving global biogeochemical cycles often remain elusive. DNA-based stable isotope probing (DNA-SIP) provides a powerful means to establish a direct link between biogeochemical processes and the taxonomic identities of active microorganisms ...
Zhongjun, Jia +2 more
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DNA Clutch Probes for Circulating Tumor DNA Analysis
Journal of the American Chemical Society, 2016Progress toward the development of minimally invasive liquid biopsies of disease is being bolstered by breakthroughs in the analysis of circulating tumor DNA (ctDNA): DNA released from cancer cells into the bloodstream. However, robust, sensitive, and specific methods of detecting this emerging analyte are lacking. ctDNA analysis has unique challenges,
Jagotamoy, Das +3 more
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