Results 281 to 290 of about 3,927,360 (403)

Universal microbial diagnostics using random DNA probes. [PDF]

Sci Adv, 2016
Aghazadeh A, Lin AY, Sheikh MA, Chen AL, Atkins LM, Johnson CL, Petrosino JF, Drezek RA, Baraniuk RG.   +8 more
europepmc   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

In situ hybridization of immunoglobulin-specific RNA in single cells of the B lymphocyte lineage with radiolabelled DNA probes [PDF]

, 1986

openalex   +1 more source

High Performance DNA Probes for Perinatal Detection of Numerical Chromosome Aberrations. [PDF]

Adv Tech Biol Med, 2015
Lemke KH, Weier JF, Weier HG, Lawin-O'Brien AR.   +3 more
europepmc   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Use of single-locus DNA probes in the establishment of relatedness in wild populations [PDF]

, 1993
John F. Y. Brookfield, David T. Parkin
openalex   +1 more source

Probing the brain with DNA chips [PDF]

Nature Neuroscience, 1999
openaire   +2 more sources

Conditionally fluorescent molecular probes for detecting single base changes in double-stranded DNA.

Nature Chemistry, 2013
S. Chen, D. Zhang, Georg Seelig
semanticscholar   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Investigation of paternity establishing without the putative father using hypervariable DNA probes [PDF]

, 1990
Tsuyoshi Yokoi, Toru Odaira, Masayuki Nata, KAORU SAGISAKA   +3 more
openalex   +1 more source