Results 281 to 290 of about 3,796,516 (329)

Scanometric DNA array detection with nanoparticle probes.

Science, 2000
A method for analyzing combinatorial DNA arrays using oligonucleotide-modified gold nanoparticle probes and a conventional flatbed scanner is described here.
T. Taton, C. Mirkin, R. Letsinger
semanticscholar   +1 more source

A graphene-based biosensing platform based on the release of DNA probes and rolling circle amplification.

ACS Nano, 2014
We report a versatile biosensing platform capable of achieving ultrasensitive detection of both small-molecule and macromolecular targets. The system features three components: reduced graphene oxide for its ability to adsorb single-stranded DNA ...
Meng Liu, Jinping Song, S. Shuang, C. Dong, J. Brennan, Yingfu Li   +5 more
semanticscholar   +1 more source

DNA probes and automation

Current Biology, 1992
Current methods for DNA probe analysis in principle provide access to the total genetic information of any organism and permit applications in health care, for example. In practice, however, greatly improved efficiency of methods for decoding genetic information is required for both research and routine applications.
openaire   +4 more sources

Probing Mouse Origins with Random DNA Probes

1988
Until not so long ago, many villages and towns used to have their own chroniclers who took it upon themselves to record for posterity those events which they believed to be the most important in the life of the community. They were, of course, no professionals; they were farmers, bakers, shoemakers, or pursued whatever occupation happened to be in ...
Masanori Kasahara, Vladimir Vincek, Jan Klein, Jan Klein, Felipe Figueroa   +4 more
openaire   +3 more sources

Multiplex ligation-dependent probe amplification (MLPA) for ultrasensitive multiplexed microRNA detection using ribonucleotide-modified DNA probes.

Chemical Communications, 2013
Using the ribonucleotide-modified DNA probes, multiple microRNAs can be simultaneously detected in one ligation-based PCR reaction. As low as 0.2 fM microRNA can be accurately detected with high specificity.
Pengbo Zhang, Ye Liu, Yajing Zhang, Chenghui Liu, Zhibin Wang, Zhengping Li   +5 more
semanticscholar   +1 more source

Fluorescent silver nanoclusters as DNA probes.

Nanoscale, 2013
Fluorescent silver nanoclusters (few atoms, quantum sized) have attracted much attention as promising substitutes for conventional fluorophores. Due to their unique environmental sensitivities, new fluorescent probes have been developed based on silver ...
J. Obliosca, Cong Liu, H. Yeh
semanticscholar   +1 more source

Absolute and direct microRNA quantification using DNA-gold nanoparticle probes.

Journal of the American Chemical Society, 2014
DNA-gold nanoparticle probes are implemented in a simple strategy for direct microRNA (miRNA) quantification. Fluorescently labeled DNA-probe strands are immobilized on PEGylated gold nanoparticles (AuNPs).
Federica Degliangeli, Prakash G. Kshirsagar, V. Brunetti, P. Pompa, R. Fiammengo   +4 more
semanticscholar   +1 more source

Characterization of DNA Probes Immobilized on Gold Surfaces

, 1997
We have characterized thiol-derivatized, single-stranded DNA (5‘-HS-(CH2)6-CAC GAC GTT GTA AAA CGA CGG CCA G-3‘, abbreviated HS-ssDNA) attached to gold via a sulfur−gold linkage using X-ray photoelectron spectroscopy (XPS), ellipsometry, and 32P ...
T. Herne, M. Tarlov
semanticscholar   +1 more source

Array-Based Electrical Detection of DNA with Nanoparticle Probes

Science, 2002
A DNA array detection method is reported in which the binding of oligonucleotides functionalized with gold nanoparticles leads to conductivity changes associated with target-probe binding events.
So-Jung Park, T. Taton, C. Mirkin
semanticscholar   +1 more source

Internal Labeling of DNA Probes

2003
Ralph Rapley and BimalD.M. Theophilus, 'Internal labeling of DNA Probes' in R. Rapley and B. D. M. Theophilus, eds., PCR Mutation Detection Protocols (Totowa: Humana Press 2002) ISBN: 978-0-89603-617-8, eISBN: 978-1-59259-273-9, DOI: 10.1385/1-59259-273-2:013 © 2002 Humana Press Inc., Totowa, NJ.
Bimal D. M. Theophilus, Ralph Rapley
openaire   +3 more sources