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Probing Mouse Origins with Random DNA Probes

1988
Until not so long ago, many villages and towns used to have their own chroniclers who took it upon themselves to record for posterity those events which they believed to be the most important in the life of the community. They were, of course, no professionals; they were farmers, bakers, shoemakers, or pursued whatever occupation happened to be in ...
J, Klein   +3 more
openaire   +2 more sources

Probing the Security of DNA Origami

2018 IEEE International Symposium on Software Reliability Engineering Workshops (ISSREW), 2018
DNA origami is a method used to program the self-assembly of nanoscale computational systems. The contribution of this paper is to probe the security of a canonical DNA origami that is often reused. The paper describes the techniques we used to design probes whose input targets the origami systems' integrity.
Chase Koehler   +3 more
openaire   +2 more sources

Probing DNA Structure With Nanoparticles

2005
Semiconductor nanoparticles, also known as quantum dots, are receiving increasing attention for their biological applications. These nanomaterials are photoluminescent and are being developed both as dyes and as sensors. Here we describe our "sensor" use of quantum dots to detect different intrinsic DNA structures.
Rahina, Mahtab, Catherine J, Murphy
openaire   +2 more sources

Enzyme-Labeled DNA Probes

2003
Many research workers and clinicians working in routine laboratories are now using the "tools" developed by molecular biologists over the past 10 years to produce DNA sequences that can be used as probes to detect specific genes. Thus it is possible to screen food for salmonella (1) or other organisms in a test much more quickly than conventional ...
J L, Woodhead   +3 more
openaire   +2 more sources

DNA stable-isotope probing

Nature Protocols, 2007
Stable-isotope probing is a method used in microbial ecology that provides a means by which specific functional groups of organisms that incorporate particular substrates are identified without the prerequisite of cultivation. Stable-isotope-labeled carbon (13C) or nitrogen (15N) sources are assimilated into microbial biomass of environmental samples ...
Neufeld, Josh D.   +6 more
openaire   +4 more sources

Small DNA circles as probes of DNA topology

Biochemical Society Transactions, 2013
Small DNA circles can occur in Nature, for example as protein-constrained loops, and can be synthesized by a number of methods. Such small circles provide tractable systems for the study of the structure, thermodynamics and molecular dynamics of closed-circular DNA.
Andrew D, Bates   +4 more
openaire   +2 more sources

Internal Labeling of DNA Probes

2003
Ralph Rapley and BimalD.M. Theophilus, 'Internal labeling of DNA Probes' in R. Rapley and B. D. M. Theophilus, eds., PCR Mutation Detection Protocols (Totowa: Humana Press 2002) ISBN: 978-0-89603-617-8, eISBN: 978-1-59259-273-9, DOI: 10.1385/1-59259-273-2:013 © 2002 Humana Press Inc., Totowa, NJ.
Ralph, Rapley, Bimal D M, Theophilus
openaire   +2 more sources

Probing RNA Translocases with DNA

2014
For some helicases, it is possible to investigate RNA translocase activity on DNA substrates because the enzyme acts on both substrates. Potassium permanganate (KMnO4) footprinting is a method used to chemically probe the conformation of DNA as well as the binding of proteins.
Kimberly A, Reynolds   +2 more
openaire   +2 more sources

DNA Probes in Diagnostic Pathology

American Journal of Clinical Pathology, 1988
Molecular pathology has become firmly established as a distinctive discipline in medicine. It has introduced radical changes in concepts of disease causation and in classification of disease states affecting humans and other organisms. In addition, molecular pathology represents a "new" diagnostic technology with many potentials that have been ...
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Nanoparticles and DNA Probes Based on DNA‐Fluorophore Conjugates

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Abdalla, M.   +3 more
openaire   +3 more sources

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