Results 241 to 250 of about 528,873 (274)

Impact of DNA repair deficiency on sensitivity to antibody-drug conjugate (ADC) payloads in bladder cancer. [PDF]

Bladder Cancer
P Shanmugam S, Zhou Y, Stelter I, Hanlon T, Bekele RT, Bellmunt J, Szallasi Z, Mouw KW.   +7 more
europepmc   +1 more source

Preferential DNA Repair in Expressed Genes

, 1987
Philip C. Hanawalt
openalex   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Investigating Chromosomal Radiosensitivity in Inborn Errors of Immunity: Insights from DNA Repair Disorders and Beyond. [PDF]

J Clin Immunol
Beyls E, Duthoo E, Backers L, Claes K, RAPID Clinicians, De Bruyne M, Pottie L, Bordon V, Bonroy C, Tavernier SJ, Claes KBM, Vral A, Baeyens A, Haerynck F.   +13 more
europepmc   +1 more source

Novel Biologically Active Glass Fiber Functionalized Using Magnesium Phosphate Cement Promotes Bone and Vascular Regeneration

Advanced Biology, EarlyView.
In this study, a new type of bioactive glass fiber ‐based composite magnesium phosphate bone cement is prepared and verified that its mechanical strength and biological properties. In addition, the cement may have played a biologically active role in the Notch and HIF signaling pathways.
Yuzheng Lu, Yanbo Shan, Yingjie Xiong, Jianting Ye, Yanbin Wu, Jipeng Song, Yao Zhang, Wancheng Lin, Haoye Meng, Wenjing Xu, Jiang Peng, Qiang Lu, Lixiang Ding   +12 more
wiley   +1 more source

Unveiling FRG1's DNA repair role in breast cancer. [PDF]

Sci Rep
Shubhanjali S, Mohapatra T, Khan R, Dixit M.   +3 more
europepmc   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Broad repression of DNA repair genes in senescent cells identified by integration of transcriptomic data. [PDF]

Nucleic Acids Res
Frey Y, Haj M, Ziv Y, Elkon R, Shiloh Y.
europepmc   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Screening Mammography and Breast Cancer: Variation in Risk with Rare Deleterious or Predicted Deleterious Variants in DNA Repair Genes. [PDF]

Cancers (Basel)
Ribeiro-Guerra M, Dondon MG, Eon-Marchais S, Le Gal D, Beauvallet J, Mebirouk N, Belotti M, Cavaciuti E, Adenis-Lavignasse C, Audebert-Bellanger S, Berthet P, Bonadona V, Buecher B, Caron O, Cavaille M, Chiesa J, Colas C, Coupier I, Delnatte C, Dreyfus H, Fajac A, Fert-Ferrer S, Fricker JP, Gauthier-Villars M, Gesta P, Giraud S, Gladieff L, Lasset C, Lejeune-Dumoulin S, Limacher JM, Longy M, Lortholary A, Luporsi E, Maugard CM, Mortemousque I, Nambot S, Noguès C, Pujol P, Venat-Bouvet L, Soubrier F, Tinat J, Tardivon A, Lesueur F, Stoppa-Lyonnet D, Andrieu N.   +44 more
europepmc   +1 more source