Results 241 to 250 of about 3,810,652 (392)

DNA Repair in Cancer [PDF]

Journal of Oncology, 2019
Zhihua Kang, Qingyuan Yang, Yintao Li
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

The CIP2A-TOPBP1 axis facilitates mitotic DNA repair via MiDAS and MMEJ. [PDF]

Nat Commun
Martin PR, Nieminuszczy J, Kozik Z, Jakub N, Kowalski S, Lecot M, Vorhauser J, Lane KA, Kanellou A, Mansfeld J, Pearl LH, Oliver AW, Downs JA, Choudhary JS, Day M, Niedzwiedz W.   +15 more
europepmc   +1 more source

DNA Repair Protein OGG1 in Pulmonary Infection and Other Inflammatory Lung Diseases [PDF]

, 2019
Ping Lin, Qinqin Pu, Shugang Qin, Jacob Schettler, Mariah Thoemke, Guoping Li, Jianxin Jiang, Min Wu   +7 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

PARP1 and PARylation facilitate transcription-coupled DNA repair by stabilizing the CSB-RNAPII complex. [PDF]

Nucleic Acids Res
Robu M, Shah RG, van den Heuvel D, Coulombe Y, Bazin M, van der Woude M, Kragten A, Lans H, Pascal JM, Masson JY, Luijsterburg MS, Shah GM.   +11 more
europepmc   +1 more source

Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signaling [PDF]

, 2019
Ruoyi Qiu, Vanessa DeRocco, Credle Harris, Anushi Sharma, Manju Hingorani, Dorothy A. Erie, Keith Weninger   +6 more
openalex   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Regulation of DNA repair gene expression by PRMT5. [PDF]

MicroPubl Biol
Bliss H, Bouley RA, Petreaca RC.
europepmc   +1 more source

Detection and imaging of the free radical DNA in cells--Site-specific radical formation induced by Fenton chemistry and its repair in cellular DNA as seen by electron spin resonance, immuno-spin trapping and confocal microscopy

, 2012
Soumen Bhattacharjee, Saurabh Chatterjee, Jiansheng Jiang, Birandra K. Sinha, Ronald P. Mason   +4 more
openalex   +1 more source