Results 261 to 270 of about 3,810,652 (392)

The role of nuclear receptor co-activator 4 in erythropoiesis (Reply to Nai et al.)

Haematologica, 2019
Naiara Santana-Codina, Sebastian Gableske, Mark D. Fleming, J. Wade Harper, Alec C. Kimmelman, Joseph D. Mancias   +5 more
doaj   +1 more source

Melatonin suppresses cancer cell proliferation, DNA repair and expression of the oncogene TRIP13. [PDF]

Cell Death Discov
Liu W, van Pelt AMM, Hamer G.
europepmc   +1 more source

The Path to DNA Repair [PDF]

Environmental Health Perspectives, 1999
openaire   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Dietary Antioxidants Influence IER5 Activation and DNA Repair: Implications for Radioprotection and Healthy Aging. [PDF]

Antioxidants (Basel)
Novotný P, Laknerová I, Jakubek M, Petrusová J.   +3 more
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Repair of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage by ABC excinuclease.

, 2020
B Van Houten, A Sancar
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Downregulation of ZFP36L1 contributes to methotrexate resistance in osteosarcoma through enhanced NHEJ DNA repair mechanisms. [PDF]

Cell Death Dis
Zhuang J, Ma M, Yang B, Liu Y, Mi R, Yang W, Lu Y, Yu H, Wu W, Song Y, Wang P, Li H.   +11 more
europepmc   +1 more source

Repair of a DNA-Protein Crosslink by Replication-Coupled Proteolysis [PDF]

, 2014
Julien P. Duxin, James M. Dewar, Hasan Yardimci, Johannes C. Walter   +3 more
openalex   +1 more source