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ATR, a DNA damage kinase, modulates DNA replication timing in Leishmania major
da Silva GLA+4 more
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DNA replication fork stabilization and restart mechanisms revealed by biochemical reconstitution
Canal B+4 more
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The mechanism of checkpoint-dependent DNA replication fork stabilization in human cells
Bertolin AP+6 more
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DNA replication stress as a hallmark of cancer.
Annual Review of Pathology, 2015Human cancers share properties referred to as hallmarks, among which sustained proliferation, escape from apoptosis, and genomic instability are the most pervasive. The sustained proliferation hallmark can be explained by mutations in oncogenes and tumor
Morgane Macheret, T. Halazonetis
semanticscholar +1 more source
DNA replication in eukaryotic cells.
Annual Review of Biochemistry, 2002The maintenance of the eukaryotic genome requires precisely coordinated replication of the entire genome each time a cell divides. To achieve this coordination, eukaryotic cells use an ordered series of steps to form several key protein assemblies at ...
S. Bell, Anindya Dutta
semanticscholar +1 more source
1986
Each daughter Cell produced on Cell division contains an identical copy of the genetic material. Since DNA carries the genetic blueprint of the Cell encoded in the sequence of nucleotides, the question as to how DNA is reproduced in the Cell has attracted a great deal of attention.
Roger L. P. Adams+2 more
openaire +2 more sources
Each daughter Cell produced on Cell division contains an identical copy of the genetic material. Since DNA carries the genetic blueprint of the Cell encoded in the sequence of nucleotides, the question as to how DNA is reproduced in the Cell has attracted a great deal of attention.
Roger L. P. Adams+2 more
openaire +2 more sources
Science, 1982
Monoclonal antibodies specific for 5-bromodeoxyuridine have been produced and applied in detecting low levels of DNA replication on a cell-by-cell basis in vitro.
H. Gratzner
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Monoclonal antibodies specific for 5-bromodeoxyuridine have been produced and applied in detecting low levels of DNA replication on a cell-by-cell basis in vitro.
H. Gratzner
semanticscholar +1 more source