Results 1 to 10 of about 251,590 (219)

The new normal? Redaction bias in biomedical science

Royal Society Open Science, 2021
A concerning amount of biomedical research is not reproducible. Unreliable results impede empirical progress in medical science, ultimately putting patients at risk.
David Robert Grimes, James Heathers
doaj   +1 more source

LZS bioactive glass-ceramic scaffolds: Colloidal processing, foam replication technique and mechanical properties to bone tissue engineering

Open Ceramics, 2022
Scaffolds are used in bone replacement because present biocompatibility, three-dimensional structure, and high porosity. However, despite the efforts, there are still significant barriers to the development of reliable, synthetic scaffolds to repair ...
Natália Morelli Possolli, Fabiano Raupp-Pereira, Oscar Rubem Klegues Montedo, Sabrina Arcaro   +3 more
doaj   +1 more source

Probabilistic model based on circular statistics for quantifying coverage depth dynamics originating from DNA replication [PDF]

PeerJ, 2020
Background With the development of DNA sequencing technology, static omics profiling in microbial communities, such as taxonomic and functional gene composition determination, has become possible.
Shinya Suzuki, Takuji Yamada
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A Semi-Static Replication Method for Bermudan Swaptions under an Affine Multi-Factor Model

Risks, 2023
We present a semi-static replication algorithm for Bermudan swaptions under an affine, multi-factor term structure model. In contrast to dynamic replication, which needs to be continuously updated as the market moves, a semi-static replication needs to ...
Jori Hoencamp, Shashi Jain, Drona Kandhai   +2 more
doaj   +1 more source

A Survey on the Attitudes Towards and Perception of Reproducibility and Replicability in Sports and Exercise Science

Communications in Kinesiology, 2023
There are formal calls for increased reproducibility and replicability in sports and exercise science, yet there is minimal information on the overall knowledge of these concepts at a field-wide level.
Jennifer Murphy, Cristian Mesquida, Joe Warne   +2 more
doaj   +1 more source

An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies. [PDF]

PLoS Genetics, 2015
Characterizing the distribution of effects from genome-wide genotyping data is crucial for understanding important aspects of the genetic architecture of complex traits, such as number or proportion of non-null loci, average proportion of phenotypic ...
Wesley K Thompson, Yunpeng Wang, Andrew J Schork, Aree Witoelar, Verena Zuber, Shujing Xu, Thomas Werge, Dominic Holland, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Ole A Andreassen, Anders M Dale   +10 more
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Statistical heartburn: an attempt to digest four pizza publications from the Cornell Food and Brand Lab

BMC Nutrition, 2017
Background We present the results of a reanalysis of four articles from the Cornell Food and Brand Lab based on data collected from diners at an Italian restaurant buffet.
Tim van der Zee, Jordan Anaya, Nicholas J. L. Brown   +2 more
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Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics

Frontiers in Genetics, 2016
Genome-wide Association Studies (GWAS) result in millions of summary statistics (``z-scores'') for single nucleotide polymorphism (SNP) associations with phenotypes.
Dominic eHolland, Dominic eHolland, Yunpeng eWang, Yunpeng eWang, Yunpeng eWang, Yunpeng eWang, Wesley K Thompson, Andrew eSchork, Chi-Hua eChen, Chi-Hua eChen, Min-Tzu eLo, Min-Tzu eLo, Aree eWitoelar, Aree eWitoelar, Thomas eWerge, Michael eO'Donovan, Ole A Andreassen, Ole A Andreassen, Anders M. Dale, Anders M. Dale, Anders M. Dale, Anders M. Dale   +21 more
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Replicated Spatial Point Pattern Analyses for Ecological Inference: A Tutorial Using the RSPPlme4 Package in R

Frontiers in Forests and Global Change, 2022
The analysis of spatial point patterns has greatly advanced our understanding of ecological processes. However, the methods currently available for analyzing replicated spatial point patterns (RSPPs) are rarely used by ecologists.
Robert Bagchi, Michael C. LaScaleia, Valerie R. Milici, Dipanjana Dalui   +3 more
doaj   +1 more source

Modification of episodic memories by novel learning: a failed replication study

European Journal of Psychotraumatology, 2017
Background: After reactivation, memories can become unstable and sensitive to modification before they are restored into long-term memory. Using behavioural manipulations, reactivated memories may be disrupted via the mechanism of interference (i.e ...
Kevin van Schie, Suzanne C. van Veen, Marcel A. van den Hout, Iris M. Engelhard   +3 more
doaj   +1 more source