Biology of host-dependent restriction-modification in prokaryotes. [PDF]
Anton BP +7 more
europepmc +1 more source
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo +9 more
wiley +1 more source
Modification of Deoxyribonucleic Acid with Indole-Linked Nucleotides Induces BZ- and Z‑Conformation and Alters Its Sensitivity to Enzymatic Cleavage. [PDF]
Lingala S +8 more
europepmc +1 more source
REBASE--enzymes and genes for DNA restriction and modification
Richard J. Roberts +3 more
openalex +1 more source
Interaction of EcoRII restriction and modification enzymes with synthetic DNA fragments [PDF]
A.A. Yolov +6 more
openalex +1 more source
Emerging roles for methionine metabolism in immune cell fate and function. [PDF]
Liu S, Tang X, Huang M, Tang J, Yang Y.
europepmc +1 more source
Serum Soluble Mediator Signatures of Lupus Nephritis: Histologic Features and Response to Treatment
Objective Lupus nephritis (LN) management remains challenging, and novel noninvasive biomarkers are needed. This study quantified serum soluble mediators in the Accelerating Medicines Partnership (AMP) LN cohort to identify biomarkers of histologic features and treatment response.
Andrea Fava +48 more
wiley +1 more source
Epigenome analysis of an algae-infecting giant virus reveals a unique methylation motif catalogue. [PDF]
Truchon AR, Zinser ER, Wilhelm SW.
europepmc +1 more source
Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham +9 more
wiley +1 more source
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang +9 more
wiley +1 more source

