Results 71 to 80 of about 2,690,595 (341)

A new repetitive DNA sequence from Trypanosoma cruzi

Memorias do Instituto Oswaldo Cruz, 1991
Tandemly repeated DNA sequences are found in the genome of higher eukaryotes, and have also been demonstrated in Trypanosoma cruzi. Repeated DNA sequences are potentially useful for the diagnostic detection of T. cruzi (A.
Leila de Mendonça-Lima, Yara M. Traub-Cseko   +1 more
doaj   +1 more source

Information decomposition of symbolic sequences

, 2003
We developed a non-parametric method of Information Decomposition (ID) of a content of any symbolical sequence. The method is based on the calculation of Shannon mutual information between analyzed and artificial symbolical sequences, and allows the ...
Adams, Almirantis, Audi, Benson, Benson, Chaley, Chechetkin, Cole, Conway, Coward, Dodin, Dodin, E.V. Korotkov, Fraser, Glaser, Grosse, Heringa, Herren, Hertz, Herzel, Jackson, Junker, Korotkova, Kullback, Lobzin, Lotman, M.A. Korotkova, Margot, Marple, McLachlan, N.A. Kudryashov, Ng, Pennisi, Presta, Rackovsky, Ramakrishna, Rashid, Silverman, Stoesser, Tiwari, Tomb, Trifonov, Venter, Voss, Wang, Weiss, Yaglom, Zirmunsky   +47 more
core   +1 more source

DNA editing in DNA/RNA hybrids by adenosine deaminases that act on RNA. [PDF]

, 2017
Adenosine deaminases that act on RNA (ADARs) carry out adenosine (A) to inosine (I) editing reactions with a known requirement for duplex RNA. Here, we show that ADARs also react with DNA/RNA hybrid duplexes.
Beal, Peter A, Lorenzo, Claire, Zheng, Yuxuan   +2 more
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Recognition of DNA Termini by the C-Terminal Region of the Ku80 and the DNA-Dependent Protein Kinase Catalytic Subunit. [PDF]

PLoS ONE, 2015
DNA double strand breaks (DSBs) can be generated by endogenous cellular processes or exogenous agents in mammalian cells. These breaks are highly variable with respect to DNA sequence and structure and all are recognized in some context by the DNA ...
Derek S Woods, Catherine R Sears, John J Turchi   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A DNA Structure-Based Bionic Wavelet Transform and Its Application to DNA Sequence Analysis

Applied Bionics and Biomechanics, 2003
DNA sequence analysis is of great significance for increasing our understanding of genomic functions. An important task facing us is the exploration of hidden structural information stored in the DNA sequence.
Fei Chen, Yuan-Ting Zhang
doaj   +1 more source

Investigation of DNA-protein Sequence-Specific Interactions with a ds-DNA Array

Molecules, 2005
The sequence specific recognitions between DNAs and proteins play important roles in many biological functions. The use of double-stranded DNA arrays (ds-DNA arrays) for studying sequence specific recognition between DNAs and proteins is a promising ...
Zuhong Lu, Quanjun Liu, Tongxiang Li, Jinke Wang, Qinyu Ge, Yunfei Bai   +5 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Compressing DNA sequence databases with coil

BMC Bioinformatics, 2008
Background Publicly available DNA sequence databases such as GenBank are large, and are growing at an exponential rate. The sheer volume of data being dealt with presents serious storage and data communications problems.
Hendy Michael D, White W Timothy J
doaj   +1 more source